PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Chlamydomonas reinhardtii
bZIP Family
Species TF ID Description
Cre01.g051174.t1.1bZIP family protein
Cre05.g238250.t1.2bZIP family protein
Cre06.g310500.t1.2bZIP family protein
Cre07.g318050.t1.2bZIP family protein
Cre07.g321550.t1.2bZIP family protein
Cre07.g344668.t1.1bZIP family protein
Cre09.g413050.t1.1bZIP family protein
Cre10.g438850.t1.2bZIP family protein
Cre10.g454850.t1.2bZIP family protein
Cre12.g489000.t1.1bZIP family protein
Cre12.g501600.t1.2bZIP family protein
Cre12.g510200.t1.2bZIP family protein
Cre12.g557300.t1.1bZIP family protein
Cre13.g568350.t1.1bZIP family protein
Cre13.g590350.t1.2bZIP family protein
Cre14.g631750.t1.1bZIP family protein
Cre14.g631750.t2.1bZIP family protein
Cre16.g692250.t1.1bZIP family protein
Cre17.g746547.t1.1bZIP family protein
bZIP Family Introduction

The bZIP domain consists of two structural features located on a contiguous alpha-helix: first, a basic region of ~ 16 amino acid residues containing a nuclear localization signal followed by an invariant N-x7-R/K motif that contacts the DNA; and, second, a heptad repeat of leucines or other bulky hydrophobic amino acids positioned exactly nine amino acids towards the C-terminus, creating an amphipathic helix. To bind DNA, two subunits adhere via interactions between the hydrophobic sides of their helices, which creates a superimposing coiled-coil structure. The ability to form homo- and heterodimers is influenced by the electrostatic attraction and repulsion of polar residues flanking the hydrophobic interaction surface of the helices.

Plant bZIP proteins preferentially bind to DNA sequences with an ACGT core. Binding specificity is regulated by flanking nucleotides. Plant bZIPs preferentially bind to the A-box (TACGTA), C-box (GACGTC) and G-box (CACGTG), but there are also examples of nonpalindromic binding sites.

Jakoby M, Weisshaar B, Droge-Laser W, Vicente-Carbajosa J, Tiedemann J, Kroj T, Parcy F
bZIP transcription factors in Arabidopsis.
Trends Plant Sci, 2002. 7(3): p. 106-11.
PMID: 11906833