PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Cucumis melo
ARF Family
Species TF ID Description
MELO3C002771P1ARF family protein
MELO3C003768P1ARF family protein
MELO3C003768P2ARF family protein
MELO3C003938P1ARF family protein
MELO3C005761P2ARF family protein
MELO3C005761P3ARF family protein
MELO3C007104P1ARF family protein
MELO3C007251P1ARF family protein
MELO3C007251P2ARF family protein
MELO3C011372P1ARF family protein
MELO3C014232P1ARF family protein
MELO3C016272P1ARF family protein
MELO3C016272P2ARF family protein
MELO3C019801P1ARF family protein
MELO3C022932P1ARF family protein
MELO3C024138P1ARF family protein
MELO3C024138P2ARF family protein
MELO3C025070P1ARF family protein
MELO3C025070P2ARF family protein
MELO3C025758P1ARF family protein
MELO3C025758P2ARF family protein
MELO3C025777P1ARF family protein
MELO3C026161P1ARF family protein
MELO3C026161P2ARF family protein
MELO3C026161P3ARF family protein
ARF Family Introduction

Auxin response factors (ARF) are transcription factors that regulate the expression of auxin response genes. ARFs bind with specificity to TGTCTC auxin response elements (AuxRE) in promoters of these genes and function in combination with Aux/IAA (auxin/indole acetic acid) repressors, which dimerize with ARF activators in an auxin-regulated manner.

Most ARFs consist of an amino-terminal DNA-binding domain (DBD), a middle region that functions as an activation domain (AD) or repression domain (RD), and a carboxy-terminal dimerization domain (CTD). The ARF DBD is classified as a plant-specific B3-type, but requires additional amino-terminal and carboxy-terminal amino acids for efficient in vitro binding to TGTCTC AuxREs.

The ARF ADs and RDs are located just carboxy-terminal to the DBDs and contain biased amino acid sequences. ARF ADs are enriched in glutamine along with serine and leucine residues, while ARF RDs are enriched in serine, proline, leucine and glycine residues.

Guilfoyle TJ, Hagen G.
Auxin response factors.
Curr Opin Plant Biol, 2007. 10(5): p. 453-60.
PMID: 17900969