PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Citrullus lanatus
bZIP Family
Species TF ID Description
Cla000383bZIP family protein
Cla002873bZIP family protein
Cla004308bZIP family protein
Cla005880bZIP family protein
Cla007293bZIP family protein
Cla007950bZIP family protein
Cla007982bZIP family protein
Cla008141bZIP family protein
Cla008649bZIP family protein
Cla008839bZIP family protein
Cla008917bZIP family protein
Cla009927bZIP family protein
Cla009958bZIP family protein
Cla010797bZIP family protein
Cla011083bZIP family protein
Cla011295bZIP family protein
Cla011901bZIP family protein
Cla013418bZIP family protein
Cla013666bZIP family protein
Cla013813bZIP family protein
Cla013824bZIP family protein
Cla014048bZIP family protein
Cla014195bZIP family protein
Cla014247bZIP family protein
Cla014501bZIP family protein
Cla014572bZIP family protein
Cla014803bZIP family protein
Cla015019bZIP family protein
Cla015138bZIP family protein
Cla015627bZIP family protein
Cla015828bZIP family protein
Cla015873bZIP family protein
Cla015874bZIP family protein
Cla016019bZIP family protein
Cla016247bZIP family protein
Cla016491bZIP family protein
Cla016581bZIP family protein
Cla017361bZIP family protein
Cla017444bZIP family protein
Cla017522bZIP family protein
Cla017696bZIP family protein
Cla017709bZIP family protein
Cla018535bZIP family protein
Cla019809bZIP family protein
Cla020278bZIP family protein
Cla020334bZIP family protein
Cla020795bZIP family protein
Cla020959bZIP family protein
Cla021184bZIP family protein
Cla021868bZIP family protein
Cla021871bZIP family protein
Cla022056bZIP family protein
Cla022235bZIP family protein
Cla022315bZIP family protein
Cla022469bZIP family protein
Cla022580bZIP family protein
Cla022644bZIP family protein
Cla022943bZIP family protein
Cla023140bZIP family protein
Cla023348bZIP family protein
Cla023484bZIP family protein
bZIP Family Introduction

The bZIP domain consists of two structural features located on a contiguous alpha-helix: first, a basic region of ~ 16 amino acid residues containing a nuclear localization signal followed by an invariant N-x7-R/K motif that contacts the DNA; and, second, a heptad repeat of leucines or other bulky hydrophobic amino acids positioned exactly nine amino acids towards the C-terminus, creating an amphipathic helix. To bind DNA, two subunits adhere via interactions between the hydrophobic sides of their helices, which creates a superimposing coiled-coil structure. The ability to form homo- and heterodimers is influenced by the electrostatic attraction and repulsion of polar residues flanking the hydrophobic interaction surface of the helices.

Plant bZIP proteins preferentially bind to DNA sequences with an ACGT core. Binding specificity is regulated by flanking nucleotides. Plant bZIPs preferentially bind to the A-box (TACGTA), C-box (GACGTC) and G-box (CACGTG), but there are also examples of nonpalindromic binding sites.

Jakoby M, Weisshaar B, Droge-Laser W, Vicente-Carbajosa J, Tiedemann J, Kroj T, Parcy F
bZIP transcription factors in Arabidopsis.
Trends Plant Sci, 2002. 7(3): p. 106-11.
PMID: 11906833