PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Coffea canephora
WRKY Family
Species TF ID Description
Cc00_g06830WRKY family protein
Cc00_g13890WRKY family protein
Cc00_g21560WRKY family protein
Cc01_g14950WRKY family protein
Cc01_g18730WRKY family protein
Cc02_g01860WRKY family protein
Cc02_g02240WRKY family protein
Cc02_g05270WRKY family protein
Cc02_g05280WRKY family protein
Cc02_g15550WRKY family protein
Cc02_g22190WRKY family protein
Cc02_g25200WRKY family protein
Cc02_g38550WRKY family protein
Cc02_g38600WRKY family protein
Cc02_g39120WRKY family protein
Cc03_g00670WRKY family protein
Cc04_g05080WRKY family protein
Cc04_g15400WRKY family protein
Cc05_g04000WRKY family protein
Cc05_g08580WRKY family protein
Cc05_g09630WRKY family protein
Cc05_g14660WRKY family protein
Cc05_g15790WRKY family protein
Cc06_g02490WRKY family protein
Cc06_g03470WRKY family protein
Cc06_g15010WRKY family protein
Cc07_g00980WRKY family protein
Cc07_g03120WRKY family protein
Cc07_g03730WRKY family protein
Cc07_g06340WRKY family protein
Cc07_g16400WRKY family protein
Cc07_g16570WRKY family protein
Cc08_g06420WRKY family protein
Cc08_g07850WRKY family protein
Cc08_g07860WRKY family protein
Cc08_g11060WRKY family protein
Cc08_g15270WRKY family protein
Cc08_g15290WRKY family protein
Cc08_g15910WRKY family protein
Cc09_g01430WRKY family protein
Cc09_g03640WRKY family protein
Cc09_g07330WRKY family protein
Cc09_g08300WRKY family protein
Cc09_g09190WRKY family protein
Cc10_g04810WRKY family protein
Cc10_g06400WRKY family protein
Cc11_g12210WRKY family protein
Cc11_g12480WRKY family protein
Cc11_g17170WRKY family protein
WRKY Family Introduction

WRKY transcription factors are one of the largest families of transcriptional regulators in plants and form integral parts of signalling webs that modulate many plant processes. Here, we review recent significant progress in WRKY transcription factor research. New findings illustrate that WRKY proteins often act as repressors as well as activators, and that members of the family play roles in both the repression and de-repression of important plant processes. Furthermore, it is becoming clear that a single WRKY transcription factor might be involved in regulating several seemingly disparate processes. Mechanisms of signalling and transcriptional regulation are being dissected, uncovering WRKY protein functions via interactions with a diverse array of protein partners, including MAP kinases, MAP kinase kinases, 14-3-3 proteins, calmodulin, histone deacetylases, resistance proteins and other WRKY transcription factors. WRKY genes exhibit extensive autoregulation and cross-regulation that facilitates transcriptional reprogramming in a dynamic web with built-in redundancy.

The defining feature of WRKY transcription factors is their DNA binding domain. This is called the WRKY domain after the almost invariant WRKY amino acid sequence at the N-terminus. In a few WRKY proteins, the WRKY amino acid sequences have been replaced by WRRY, WSKY, WKRY, WVKY or WKKY. The WRKY domain is about 60 residues in length, and as well as containing the WRKY signature it also has an atypical zinc-finger structure at the C-terminus. The zinc-finger structure is either Cx4-5Cx22-23HxH or Cx7Cx23HxC. Initially, in the absence of a complete gene family from any plant species, the WRKY transcription factors were divided into three groups based on the number of WRKY domains (two domains in Group I proteins and one in the others) and the structure of their zinc fingers (C2HC in Group III proteins).

Rushton PJ, Somssich IE, Ringler P, Shen QJ.
WRKY transcription factors.
Trends Plant Sci, 2010. 15(5): p. 247-58.
PMID: 20304701