PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Coffea canephora
ARF Family
Species TF ID Description
Cc00_g00210ARF family protein
Cc00_g12260ARF family protein
Cc01_g11020ARF family protein
Cc01_g11410ARF family protein
Cc02_g11300ARF family protein
Cc02_g14070ARF family protein
Cc02_g39520ARF family protein
Cc03_g11270ARF family protein
Cc05_g00510ARF family protein
Cc06_g03950ARF family protein
Cc06_g12540ARF family protein
Cc07_g12410ARF family protein
Cc08_g16330ARF family protein
Cc09_g08740ARF family protein
Cc10_g01900ARF family protein
ARF Family Introduction

Auxin response factors (ARF) are transcription factors that regulate the expression of auxin response genes. ARFs bind with specificity to TGTCTC auxin response elements (AuxRE) in promoters of these genes and function in combination with Aux/IAA (auxin/indole acetic acid) repressors, which dimerize with ARF activators in an auxin-regulated manner.

Most ARFs consist of an amino-terminal DNA-binding domain (DBD), a middle region that functions as an activation domain (AD) or repression domain (RD), and a carboxy-terminal dimerization domain (CTD). The ARF DBD is classified as a plant-specific B3-type, but requires additional amino-terminal and carboxy-terminal amino acids for efficient in vitro binding to TGTCTC AuxREs.

The ARF ADs and RDs are located just carboxy-terminal to the DBDs and contain biased amino acid sequences. ARF ADs are enriched in glutamine along with serine and leucine residues, while ARF RDs are enriched in serine, proline, leucine and glycine residues.

Guilfoyle TJ, Hagen G.
Auxin response factors.
Curr Opin Plant Biol, 2007. 10(5): p. 453-60.
PMID: 17900969