PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Cicer arietinum
NF-YA Family
Species TF ID Description
XP_004486451.1NF-YA family protein
XP_004486452.1NF-YA family protein
XP_004486453.1NF-YA family protein
XP_004494259.1NF-YA family protein
XP_004497643.1NF-YA family protein
XP_004500196.1NF-YA family protein
XP_004500197.1NF-YA family protein
XP_004510428.1NF-YA family protein
XP_004510429.1NF-YA family protein
XP_004510989.1NF-YA family protein
XP_004513462.1NF-YA family protein
XP_004513464.1NF-YA family protein
XP_004513467.1NF-YA family protein
XP_012570124.1NF-YA family protein
XP_012570383.1NF-YA family protein
XP_012571278.1NF-YA family protein
XP_012571402.1NF-YA family protein
XP_012574919.1NF-YA family protein
XP_012574920.1NF-YA family protein
XP_012574921.1NF-YA family protein
NF-YA Family Introduction

NF-Y transcription factors are likely found in all eukaryotes and have roles in the regulation of diverse genes (McNabb et al., 1995; Edwards et al., 1998; Maity and de Crombrugghe, 1998; Mantovani, 1999). In mammals, where their biochemistry is well described, the NF-Y transcription factor complex is composed of three unique subunits: NF-YA, NF-YB, and NF-YC. Assembly of the NF-Y heterotrimer in mammals follows a strict, stepwise pattern (Sinha et al., 1995, 1996). Initially, a heterodimer is formed in the cytoplasm between the subunits NF-YB and NF-YC. This dimer then translocates to the nucleus, where the third subunit, NF-YA, is recruited to generate the mature, heterotrimeric NF-Y transcription factor (Frontini et al., 2004; Kahle et al., 2005). Mature NF-Y binds promoters with the core pentamer nucleotide sequence CCAAT, and this can result in either positive or negative transcriptional regulation(Peng and Jahroudi, 2002, 2003; Ceribelli et al., 2008).

NF-YA proteins are characterized by the presence of Gln(Q)- and Ser/Thr(S/T)-rich NH2 termini, a subunit interaction domain (NF-YB/NF-YC interaction), and a DNA-binding domain (Olesen and Guarente, 1990; Maity and de Crombrugghe, 1992; Xing et al., 1993, 1994). The protein interaction and DNA binding domains are well conserved between plant and other eukaryote lineages.

Siefers N, Dang KK, Kumimoto RW, Bynum WE 4th, Tayrose G, Holt BF 3rd.
Tissue-specific expression patterns of Arabidopsis NF-Y transcription factors suggest potential for extensive combinatorial complexity.
Plant Physiol, 2009. 149(2): p. 625-41.
PMID: 19019982