PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Cicer arietinum
FAR1 Family
Species TF ID Description
XP_004485421.1FAR1 family protein
XP_004485422.1FAR1 family protein
XP_004486100.1FAR1 family protein
XP_004486914.1FAR1 family protein
XP_004486915.1FAR1 family protein
XP_004486917.1FAR1 family protein
XP_004486918.1FAR1 family protein
XP_004486947.1FAR1 family protein
XP_004487795.1FAR1 family protein
XP_004490690.1FAR1 family protein
XP_004491167.1FAR1 family protein
XP_004491651.1FAR1 family protein
XP_004494023.1FAR1 family protein
XP_004496070.1FAR1 family protein
XP_004496891.1FAR1 family protein
XP_004496892.1FAR1 family protein
XP_004497701.2FAR1 family protein
XP_004497702.1FAR1 family protein
XP_004498019.1FAR1 family protein
XP_004498703.1FAR1 family protein
XP_004501994.1FAR1 family protein
XP_004501995.1FAR1 family protein
XP_004506622.1FAR1 family protein
XP_004507429.2FAR1 family protein
XP_004507548.1FAR1 family protein
XP_004507549.1FAR1 family protein
XP_004507550.1FAR1 family protein
XP_004507551.1FAR1 family protein
XP_004507552.1FAR1 family protein
XP_004509897.2FAR1 family protein
XP_004511157.1FAR1 family protein
XP_004511158.1FAR1 family protein
XP_004511159.1FAR1 family protein
XP_004511160.1FAR1 family protein
XP_004514173.1FAR1 family protein
XP_004515955.1FAR1 family protein
XP_004516162.1FAR1 family protein
XP_004516271.1FAR1 family protein
XP_004516444.1FAR1 family protein
XP_012567317.1FAR1 family protein
XP_012568622.1FAR1 family protein
XP_012568958.1FAR1 family protein
XP_012569658.1FAR1 family protein
XP_012570139.1FAR1 family protein
XP_012570140.1FAR1 family protein
XP_012570143.1FAR1 family protein
XP_012570144.1FAR1 family protein
XP_012570256.1FAR1 family protein
XP_012570522.1FAR1 family protein
XP_012571074.1FAR1 family protein
XP_012571075.1FAR1 family protein
XP_012571076.1FAR1 family protein
XP_012571757.1FAR1 family protein
XP_012571758.1FAR1 family protein
XP_012572031.1FAR1 family protein
XP_012573015.1FAR1 family protein
XP_012573277.1FAR1 family protein
XP_012573278.1FAR1 family protein
XP_012574070.1FAR1 family protein
XP_012574487.1FAR1 family protein
XP_012574577.1FAR1 family protein
XP_012575559.1FAR1 family protein
FAR1 Family Introduction

We show that Arabidopsis FHY3 and FAR1, which encode two proteins related to Mutator-like transposases, act together to modulate phyA signaling by directly activating the transcription of FHY1 and FHL, whose products are essential for light-induced phyA nuclear accumulation and subsequent light responses. FHY3 and FAR1 have separable DNA binding and transcriptional activation domains that are highly conserved in Mutator-like transposases. Further, expression of FHY3 and FAR1 is negatively regulated by phyA signaling. We propose that FHY3 and FAR1 represent transcription factors that have been co-opted from an ancient Mutator-like transposase(s) to modulate phyA-signaling homeostasis in higher plants.

We next used a yeast one-hybrid assay to delineate the DNA sequences to which FHY3 and FAR1 bind. GAD-FHY3 or GAD-FAR1 fusion proteins (GAD, GAL4 transcriptional activation domain), but not GAD alone, activated the LacZ reporter genes driven by the FHY1 and FHL promoters. Deletion analysis narrowed down the FHY3/FAR1 binding site to a 39-bp promoter subfragment located on the "a" fragment for both FHY1 and FHL. Notably, these subfragments share a stretch of consensus sequence, 5'-TTCACGCGCC-3'. Mutating the core sequence "CACGCGC" of this motif (m2 and m3 for FHY1, m5 for FHL) abolished the reporter gene activation by both GAD-FHY3 and GAD-FAR1. Mutating the flanking sequences (m1 and m4) did not obviously affect the reporter gene activation by GAD-FAR1, but clearly reduced activation by GAD-FHY3. Thus, "CACGCGC" likely defines a cis-element that confers specific binding for FHY3 and FAR1 and is named FBS for FHY3-FAR1 binding site.

Lin R, Ding L, Casola C, Ripoll DR, Feschotte C, Wang H.
Transposase-derived transcription factors regulate light signaling in Arabidopsis.
Science, 2007. 318(5854): p. 1302-5.
PMID: 18033885