PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Brachypodium stacei
WOX Family
Species TF ID Description
Brast05G301000.1.pWOX family protein
Brast08G225300.1.pWOX family protein
Brast09G234700.1.pWOX family protein
Brast01G085600.1.pWOX family protein
Brast09G246200.1.pWOX family protein
Brast01G189800.1.pWOX family protein
Brast02G166000.1.pWOX family protein
Brast06G008800.1.pWOX family protein
Brast03G064000.1.pWOX family protein
Brast01G106700.1.pWOX family protein
Brast02G103200.1.pWOX family protein
Brast01G093300.1.pWOX family protein
Brast08G023500.1.pWOX family protein
WOX Family Introduction

A homeobox (HB) encodes a protein domain, the homeodomain (HD), which is a conserved 60-amino acid motif present in transcription factors found in all the eukaryotic organisms. This 60-amino acid sequence folds into a characteristic three-helix structure that is able to interact specifically with DNA. Most HDs are able to bind DNA as monomers with high affinity, through interactions made by helix III (the so-called recognition helix) and a disordered N-terminal arm located beyond helix I. The high degree of conservation of this type of domain among diverse proteins from different kingdoms indicates that this structure is crucial to maintain the HD functionality and that the role played by this domain is vital.

Ariel FD, Manavella PA, Dezar CA, Chan RL.
The true story of the HD-Zip family.
Trends Plant Sci, 2007. 12(9): p. 419-26.
PMID: 17698401

The WOX genes form a plant-specific subclade of the eukaryotic homeobox transcription factor superfamily, which is characterized by the presence of a conserved DNA-binding homeodomain. The analysis of WOX gene expression and function shows that WOX family members fulfill specialized functions in key developmental processes in plants, such as embryonic patterning, stem-cell maintenance and organ formation. These functions can be related to either promotion of cell division activity and/or prevention of premature cell differentiation.

van der Graaff E, Laux T, Rensing SA.
The WUS homeobox-containing (WOX) protein family.
Genome Biol, 2009. 10(12): p. 248.
PMID: 20067590