PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Brassica rapa
HD-ZIP Family
Species TF ID Description
XP_009150623.1HD-ZIP family protein
XP_009131444.1HD-ZIP family protein
XP_009105645.1HD-ZIP family protein
XP_009140353.1HD-ZIP family protein
XP_009112528.1HD-ZIP family protein
XP_009125018.1HD-ZIP family protein
XP_009125019.1HD-ZIP family protein
XP_009130954.1HD-ZIP family protein
XP_009121604.1HD-ZIP family protein
XP_009122282.1HD-ZIP family protein
XP_009126033.1HD-ZIP family protein
XP_009147435.1HD-ZIP family protein
XP_009130694.1HD-ZIP family protein
XP_009130625.1HD-ZIP family protein
XP_009127760.1HD-ZIP family protein
XP_009130506.1HD-ZIP family protein
XP_009147412.1HD-ZIP family protein
XP_009140396.1HD-ZIP family protein
XP_009140395.1HD-ZIP family protein
XP_009145468.1HD-ZIP family protein
XP_009142306.1HD-ZIP family protein
XP_009124619.1HD-ZIP family protein
XP_009124618.1HD-ZIP family protein
XP_009138531.1HD-ZIP family protein
XP_009143079.1HD-ZIP family protein
XP_009144501.1HD-ZIP family protein
XP_009143078.1HD-ZIP family protein
XP_009138448.1HD-ZIP family protein
XP_009138447.1HD-ZIP family protein
XP_009116721.1HD-ZIP family protein
XP_009109426.1HD-ZIP family protein
XP_009133094.1HD-ZIP family protein
XP_009142615.1HD-ZIP family protein
XP_009136844.1HD-ZIP family protein
XP_009125133.1HD-ZIP family protein
XP_009109392.1HD-ZIP family protein
XP_009110055.1HD-ZIP family protein
XP_009101427.1HD-ZIP family protein
XP_009114283.1HD-ZIP family protein
XP_009125041.1HD-ZIP family protein
XP_009114239.1HD-ZIP family protein
XP_009103496.1HD-ZIP family protein
XP_009114236.1HD-ZIP family protein
XP_009114237.1HD-ZIP family protein
XP_009129242.1HD-ZIP family protein
XP_009142335.1HD-ZIP family protein
XP_009116857.1HD-ZIP family protein
XP_009114697.1HD-ZIP family protein
XP_009114696.1HD-ZIP family protein
XP_009130555.1HD-ZIP family protein
XP_009112326.1HD-ZIP family protein
XP_009142436.1HD-ZIP family protein
XP_009130781.1HD-ZIP family protein
XP_009130780.1HD-ZIP family protein
XP_009138744.1HD-ZIP family protein
XP_009122668.1HD-ZIP family protein
XP_009122669.1HD-ZIP family protein
XP_009125518.1HD-ZIP family protein
XP_009125517.1HD-ZIP family protein
XP_009115435.1HD-ZIP family protein
XP_009143572.1HD-ZIP family protein
XP_009103762.1HD-ZIP family protein
XP_009127836.1HD-ZIP family protein
XP_009105759.1HD-ZIP family protein
XP_009127124.1HD-ZIP family protein
XP_009104428.1HD-ZIP family protein
XP_009119177.1HD-ZIP family protein
XP_009119178.1HD-ZIP family protein
XP_009119179.1HD-ZIP family protein
XP_009119180.1HD-ZIP family protein
XP_009137213.1HD-ZIP family protein
XP_009118607.1HD-ZIP family protein
XP_009118608.1HD-ZIP family protein
XP_009118609.1HD-ZIP family protein
XP_009118610.1HD-ZIP family protein
XP_009118611.1HD-ZIP family protein
XP_009134323.1HD-ZIP family protein
XP_009114536.1HD-ZIP family protein
XP_009114537.1HD-ZIP family protein
XP_009134533.1HD-ZIP family protein
XP_009108529.1HD-ZIP family protein
XP_009111469.1HD-ZIP family protein
XP_009135189.1HD-ZIP family protein
XP_009108824.1HD-ZIP family protein
XP_009135181.1HD-ZIP family protein
XP_009143747.1HD-ZIP family protein
XP_009125299.1HD-ZIP family protein
XP_009125305.1HD-ZIP family protein
XP_009143168.1HD-ZIP family protein
XP_009143166.1HD-ZIP family protein
XP_009143167.1HD-ZIP family protein
XP_009104292.1HD-ZIP family protein
XP_009141396.1HD-ZIP family protein
XP_009115139.1HD-ZIP family protein
XP_009106897.1HD-ZIP family protein
XP_009147709.1HD-ZIP family protein
XP_009107148.1HD-ZIP family protein
XP_009107147.1HD-ZIP family protein
XP_009104812.1HD-ZIP family protein
XP_009141216.1HD-ZIP family protein
XP_009141217.1HD-ZIP family protein
XP_009141218.1HD-ZIP family protein
XP_009141219.1HD-ZIP family protein
XP_009141220.1HD-ZIP family protein
XP_009141222.1HD-ZIP family protein
XP_009141223.1HD-ZIP family protein
XP_009141224.1HD-ZIP family protein
XP_009141225.1HD-ZIP family protein
XP_009141226.1HD-ZIP family protein
XP_009150087.1HD-ZIP family protein
XP_009143975.1HD-ZIP family protein
XP_009143976.1HD-ZIP family protein
XP_009143977.1HD-ZIP family protein
XP_009143974.1HD-ZIP family protein
XP_009126588.1HD-ZIP family protein
XP_009120604.1HD-ZIP family protein
XP_009120605.1HD-ZIP family protein
XP_009120606.1HD-ZIP family protein
XP_009108342.1HD-ZIP family protein
XP_009105998.1HD-ZIP family protein
XP_009110377.1HD-ZIP family protein
XP_009110376.1HD-ZIP family protein
XP_009114317.1HD-ZIP family protein
XP_009114318.1HD-ZIP family protein
XP_009114319.1HD-ZIP family protein
XP_009114320.1HD-ZIP family protein
XP_009114321.1HD-ZIP family protein
XP_009101475.1HD-ZIP family protein
XP_009101472.1HD-ZIP family protein
XP_009101473.1HD-ZIP family protein
XP_009101474.1HD-ZIP family protein
XP_009149243.1HD-ZIP family protein
XP_009121397.1HD-ZIP family protein
XP_009126177.1HD-ZIP family protein
XP_009103958.1HD-ZIP family protein
XP_009119205.1HD-ZIP family protein
XP_009119199.1HD-ZIP family protein
XP_009130351.1HD-ZIP family protein
XP_009126392.1HD-ZIP family protein
HD-ZIP Family Introduction

A homeobox (HB) encodes a protein domain, the homeodomain (HD), which is a conserved 60-amino acid motif present in transcription factors found in all the eukaryotic organisms. This 60-amino acid sequence folds into a characteristic three-helix structure that is able to interact specifically with DNA. Most HDs are able to bind DNA as monomers with high affinity, through interactions made by helix III (the so-called recognition helix) and a disordered N-terminal arm located beyond helix I. The high degree of conservation of this type of domain among diverse proteins from different kingdoms indicates that this structure is crucial to maintain the HD functionality and that the role played by this domain is vital.

Members of the HD-Zip family have a leucine zipper motif (LZ) immediately downstream of the HD. The two motifs are present in transcription factors found in species belonging to other eukaryotic kingdoms, but their association in a single protein is unique to plants. The HD is responsible for the specific binding to DNA, whereas LZ acts as a dimerization motif. HD-Zip proteins bind to DNA as dimers, and the absence of LZ absolutely abolishes their binding ability, which indicates that the relative orientation of the monomers, driven by this motif, is crucial for an efficient recognition of DNA.

Ariel FD, Manavella PA, Dezar CA, Chan RL.
The true story of the HD-Zip family.
Trends Plant Sci, 2007. 12(9): p. 419-26.
PMID: 17698401