PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Brassica rapa
E2F/DP Family
Species TF ID Description
XP_009107400.1E2F/DP family protein
XP_009107401.1E2F/DP family protein
XP_009107402.1E2F/DP family protein
XP_009107403.1E2F/DP family protein
XP_009120677.1E2F/DP family protein
XP_009122704.1E2F/DP family protein
XP_009122777.1E2F/DP family protein
XP_009126020.1E2F/DP family protein
XP_009130705.1E2F/DP family protein
XP_009130756.1E2F/DP family protein
XP_009130757.1E2F/DP family protein
XP_009130758.1E2F/DP family protein
XP_009131867.1E2F/DP family protein
XP_009133061.1E2F/DP family protein
XP_009133063.1E2F/DP family protein
XP_009141554.1E2F/DP family protein
XP_009143621.1E2F/DP family protein
XP_009143622.1E2F/DP family protein
XP_009147417.1E2F/DP family protein
XP_009149841.1E2F/DP family protein
XP_009150868.1E2F/DP family protein
XP_009150874.1E2F/DP family protein
E2F/DP Family Introduction

E2F transcription factors are a family of proteins that share a related DNA-binding domain and that bind to overlapping sets of target promoters. Most E2F proteins associate with a DP protein and form heterodimeric complexes that bind to DNA in a sequence-specific manner. E2F proteins control the temporal expression of genes that are needed for multiple processes during the cell cycle. Consequently, the level of E2F-dependent transcription is important for cell proliferation.

Different types of E2F complexes either activate or repress transcription. E2F repressor complexes suppress the transcription of their targets in quiescent cells, in differentiated cells and during the G1 phase of the cell cycle. When cells enter the cell cycle and proliferate, these repressors are disrupted and/or replaced by activator forms of E2F that promote gene expression.

van den Heuvel S, Dyson NJ.
Conserved functions of the pRB and E2F families.
Nat Rev Mol Cell Biol, 2008. 9(9): p. 713-24.
PMID: 18719710