PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Brassica oleracea
bHLH Family
Species TF ID Description
XP_013583356.1bHLH family protein
XP_013583361.1bHLH family protein
XP_013583782.1bHLH family protein
XP_013583788.1bHLH family protein
XP_013583806.1bHLH family protein
XP_013584111.1bHLH family protein
XP_013584174.1bHLH family protein
XP_013584175.1bHLH family protein
XP_013584176.1bHLH family protein
XP_013584279.1bHLH family protein
XP_013584333.1bHLH family protein
XP_013584378.1bHLH family protein
XP_013584379.1bHLH family protein
XP_013584499.1bHLH family protein
XP_013584555.1bHLH family protein
XP_013584612.1bHLH family protein
XP_013584613.1bHLH family protein
XP_013584762.1bHLH family protein
XP_013584847.1bHLH family protein
XP_013584887.1bHLH family protein
XP_013584948.1bHLH family protein
XP_013585010.1bHLH family protein
XP_013585235.1bHLH family protein
XP_013585283.1bHLH family protein
XP_013585673.1bHLH family protein
XP_013586346.1bHLH family protein
XP_013586354.1bHLH family protein
XP_013586362.1bHLH family protein
XP_013586726.1bHLH family protein
XP_013587292.1bHLH family protein
XP_013587345.1bHLH family protein
XP_013587528.1bHLH family protein
XP_013587529.1bHLH family protein
XP_013587618.1bHLH family protein
XP_013587853.1bHLH family protein
XP_013587860.1bHLH family protein
XP_013587861.1bHLH family protein
XP_013588080.1bHLH family protein
XP_013588246.1bHLH family protein
XP_013588252.1bHLH family protein
XP_013588353.1bHLH family protein
XP_013588354.1bHLH family protein
XP_013588355.1bHLH family protein
XP_013588513.1bHLH family protein
XP_013588514.1bHLH family protein
XP_013588587.1bHLH family protein
XP_013588588.1bHLH family protein
XP_013588589.1bHLH family protein
XP_013588773.1bHLH family protein
XP_013588774.1bHLH family protein
XP_013588813.1bHLH family protein
XP_013588924.1bHLH family protein
XP_013588931.1bHLH family protein
XP_013589895.1bHLH family protein
XP_013590173.1bHLH family protein
XP_013590340.1bHLH family protein
XP_013590391.1bHLH family protein
XP_013590557.1bHLH family protein
XP_013590899.1bHLH family protein
XP_013590924.1bHLH family protein
XP_013590939.1bHLH family protein
XP_013590973.1bHLH family protein
XP_013591036.1bHLH family protein
XP_013591139.1bHLH family protein
XP_013591155.1bHLH family protein
XP_013591181.1bHLH family protein
XP_013591182.1bHLH family protein
XP_013591183.1bHLH family protein
XP_013591325.1bHLH family protein
XP_013592305.1bHLH family protein
XP_013593013.1bHLH family protein
XP_013593129.1bHLH family protein
XP_013593130.1bHLH family protein
XP_013593134.1bHLH family protein
XP_013593214.1bHLH family protein
XP_013593660.1bHLH family protein
XP_013593787.1bHLH family protein
XP_013593795.1bHLH family protein
XP_013593916.1bHLH family protein
XP_013593917.1bHLH family protein
XP_013594063.1bHLH family protein
XP_013594159.1bHLH family protein
XP_013594363.1bHLH family protein
XP_013594366.1bHLH family protein
XP_013594370.1bHLH family protein
XP_013594410.1bHLH family protein
XP_013594413.1bHLH family protein
XP_013594644.1bHLH family protein
XP_013594846.1bHLH family protein
XP_013594895.1bHLH family protein
XP_013595350.1bHLH family protein
XP_013595760.1bHLH family protein
XP_013595899.1bHLH family protein
XP_013596038.1bHLH family protein
XP_013596284.1bHLH family protein
XP_013596285.1bHLH family protein
XP_013596293.1bHLH family protein
XP_013596294.1bHLH family protein
XP_013596472.1bHLH family protein
XP_013596473.1bHLH family protein
XP_013596559.1bHLH family protein
XP_013596574.1bHLH family protein
XP_013596661.1bHLH family protein
XP_013596868.1bHLH family protein
XP_013597063.1bHLH family protein
XP_013597072.1bHLH family protein
XP_013597228.1bHLH family protein
XP_013597230.1bHLH family protein
XP_013597233.1bHLH family protein
XP_013597306.1bHLH family protein
XP_013597451.1bHLH family protein
XP_013598243.1bHLH family protein
XP_013598295.1bHLH family protein
XP_013598390.1bHLH family protein
XP_013598391.1bHLH family protein
XP_013598841.1bHLH family protein
XP_013599535.1bHLH family protein
XP_013599939.1bHLH family protein
XP_013600686.1bHLH family protein
XP_013600687.1bHLH family protein
XP_013600769.1bHLH family protein
XP_013601431.1bHLH family protein
XP_013601484.1bHLH family protein
XP_013601684.1bHLH family protein
XP_013601940.1bHLH family protein
XP_013602228.1bHLH family protein
XP_013602621.1bHLH family protein
XP_013602811.1bHLH family protein
XP_013602848.1bHLH family protein
XP_013602849.1bHLH family protein
XP_013602850.1bHLH family protein
XP_013602851.1bHLH family protein
XP_013602886.1bHLH family protein
XP_013602952.1bHLH family protein
XP_013603012.1bHLH family protein
XP_013603073.1bHLH family protein
XP_013603284.1bHLH family protein
XP_013603658.1bHLH family protein
XP_013603792.1bHLH family protein
XP_013603808.1bHLH family protein
XP_013603812.1bHLH family protein
XP_013603852.1bHLH family protein
XP_013603891.1bHLH family protein
XP_013603898.1bHLH family protein
XP_013603936.1bHLH family protein
XP_013604055.1bHLH family protein
XP_013604461.1bHLH family protein
XP_013604462.1bHLH family protein
XP_013605028.1bHLH family protein
XP_013605267.1bHLH family protein
XP_013605590.1bHLH family protein
XP_013605591.1bHLH family protein
XP_013605592.1bHLH family protein
XP_013605593.1bHLH family protein
XP_013605597.1bHLH family protein
XP_013605863.1bHLH family protein
XP_013605864.1bHLH family protein
XP_013605865.1bHLH family protein
XP_013605866.1bHLH family protein
XP_013605867.1bHLH family protein
XP_013605919.1bHLH family protein
XP_013605973.1bHLH family protein
XP_013605974.1bHLH family protein
XP_013605975.1bHLH family protein
XP_013606234.1bHLH family protein
XP_013606267.1bHLH family protein
XP_013606268.1bHLH family protein
XP_013606269.1bHLH family protein
XP_013606270.1bHLH family protein
XP_013606376.1bHLH family protein
XP_013606377.1bHLH family protein
XP_013606719.1bHLH family protein
XP_013606771.1bHLH family protein
XP_013606780.1bHLH family protein
XP_013606936.1bHLH family protein
XP_013606937.1bHLH family protein
XP_013606938.1bHLH family protein
XP_013608418.1bHLH family protein
XP_013608424.1bHLH family protein
XP_013608427.1bHLH family protein
XP_013608492.1bHLH family protein
XP_013608495.1bHLH family protein
XP_013608909.1bHLH family protein
XP_013608954.1bHLH family protein
XP_013608962.1bHLH family protein
XP_013608988.1bHLH family protein
XP_013608989.1bHLH family protein
XP_013608995.1bHLH family protein
XP_013609174.1bHLH family protein
XP_013609367.1bHLH family protein
XP_013609428.1bHLH family protein
XP_013609548.1bHLH family protein
XP_013609563.1bHLH family protein
XP_013609849.1bHLH family protein
XP_013609939.1bHLH family protein
XP_013610045.1bHLH family protein
XP_013610066.1bHLH family protein
XP_013610255.1bHLH family protein
XP_013610461.1bHLH family protein
XP_013610489.1bHLH family protein
XP_013610521.1bHLH family protein
XP_013612197.1bHLH family protein
XP_013612311.1bHLH family protein
XP_013612346.1bHLH family protein
XP_013613139.1bHLH family protein
XP_013613140.1bHLH family protein
XP_013613372.1bHLH family protein
XP_013613373.1bHLH family protein
XP_013613374.1bHLH family protein
XP_013613626.1bHLH family protein
XP_013613874.1bHLH family protein
XP_013613975.1bHLH family protein
XP_013613999.1bHLH family protein
XP_013614310.1bHLH family protein
XP_013614316.1bHLH family protein
XP_013614399.1bHLH family protein
XP_013614535.1bHLH family protein
XP_013614574.1bHLH family protein
XP_013614575.1bHLH family protein
XP_013614723.1bHLH family protein
XP_013615044.1bHLH family protein
XP_013615108.1bHLH family protein
XP_013615111.1bHLH family protein
XP_013615363.1bHLH family protein
XP_013615364.1bHLH family protein
XP_013615365.1bHLH family protein
XP_013615366.1bHLH family protein
XP_013615367.1bHLH family protein
XP_013615754.1bHLH family protein
XP_013615939.1bHLH family protein
XP_013615940.1bHLH family protein
XP_013615991.1bHLH family protein
XP_013615996.1bHLH family protein
XP_013618266.1bHLH family protein
XP_013618267.1bHLH family protein
XP_013618371.1bHLH family protein
XP_013618510.1bHLH family protein
XP_013618511.1bHLH family protein
XP_013618564.1bHLH family protein
XP_013618572.1bHLH family protein
XP_013618641.1bHLH family protein
XP_013618836.1bHLH family protein
XP_013618974.1bHLH family protein
XP_013618976.1bHLH family protein
XP_013619019.1bHLH family protein
XP_013619040.1bHLH family protein
XP_013619041.1bHLH family protein
XP_013619042.1bHLH family protein
XP_013619092.1bHLH family protein
XP_013619093.1bHLH family protein
XP_013619191.1bHLH family protein
XP_013619386.1bHLH family protein
XP_013619554.1bHLH family protein
XP_013619569.1bHLH family protein
XP_013619687.1bHLH family protein
XP_013619704.1bHLH family protein
XP_013619875.1bHLH family protein
XP_013620274.1bHLH family protein
XP_013621407.1bHLH family protein
XP_013621548.1bHLH family protein
XP_013621549.1bHLH family protein
XP_013621948.1bHLH family protein
XP_013622040.1bHLH family protein
XP_013622107.1bHLH family protein
XP_013622108.1bHLH family protein
XP_013622109.1bHLH family protein
XP_013622110.1bHLH family protein
XP_013622111.1bHLH family protein
XP_013622112.1bHLH family protein
XP_013622118.1bHLH family protein
XP_013622128.1bHLH family protein
XP_013622129.1bHLH family protein
XP_013622137.1bHLH family protein
XP_013622358.1bHLH family protein
XP_013622671.1bHLH family protein
XP_013622889.1bHLH family protein
XP_013623004.1bHLH family protein
XP_013623171.1bHLH family protein
XP_013623172.1bHLH family protein
XP_013623173.1bHLH family protein
XP_013624787.1bHLH family protein
XP_013625068.1bHLH family protein
XP_013625069.1bHLH family protein
XP_013625360.1bHLH family protein
XP_013625365.1bHLH family protein
XP_013625672.1bHLH family protein
XP_013625673.1bHLH family protein
XP_013626148.1bHLH family protein
XP_013626191.1bHLH family protein
XP_013626192.1bHLH family protein
XP_013626414.1bHLH family protein
XP_013626432.1bHLH family protein
XP_013626433.1bHLH family protein
XP_013626434.1bHLH family protein
XP_013626435.1bHLH family protein
XP_013626486.1bHLH family protein
XP_013626524.1bHLH family protein
XP_013626713.1bHLH family protein
XP_013627088.1bHLH family protein
XP_013627238.1bHLH family protein
XP_013627243.1bHLH family protein
XP_013627286.1bHLH family protein
XP_013627373.1bHLH family protein
XP_013627418.1bHLH family protein
XP_013627511.1bHLH family protein
XP_013627524.1bHLH family protein
XP_013627730.1bHLH family protein
XP_013627774.1bHLH family protein
XP_013627799.1bHLH family protein
XP_013627871.1bHLH family protein
XP_013627983.1bHLH family protein
XP_013628089.1bHLH family protein
XP_013628222.1bHLH family protein
XP_013628223.1bHLH family protein
XP_013628646.1bHLH family protein
XP_013629190.1bHLH family protein
XP_013629191.1bHLH family protein
XP_013629205.1bHLH family protein
XP_013630148.1bHLH family protein
XP_013631111.1bHLH family protein
XP_013631585.1bHLH family protein
XP_013631820.1bHLH family protein
XP_013632091.1bHLH family protein
XP_013632092.1bHLH family protein
XP_013632174.1bHLH family protein
XP_013632282.1bHLH family protein
XP_013632341.1bHLH family protein
XP_013632630.1bHLH family protein
XP_013633542.1bHLH family protein
XP_013633543.1bHLH family protein
XP_013633734.1bHLH family protein
XP_013633827.1bHLH family protein
XP_013633828.1bHLH family protein
XP_013633829.1bHLH family protein
XP_013633859.1bHLH family protein
XP_013633861.1bHLH family protein
XP_013633919.1bHLH family protein
XP_013633940.1bHLH family protein
XP_013634195.1bHLH family protein
XP_013634229.1bHLH family protein
XP_013634260.1bHLH family protein
XP_013634338.1bHLH family protein
XP_013634339.1bHLH family protein
XP_013634340.1bHLH family protein
XP_013634341.1bHLH family protein
XP_013634445.1bHLH family protein
XP_013634446.1bHLH family protein
XP_013634470.1bHLH family protein
XP_013634471.1bHLH family protein
XP_013634584.1bHLH family protein
XP_013634585.1bHLH family protein
XP_013634648.1bHLH family protein
XP_013634830.1bHLH family protein
XP_013634885.1bHLH family protein
XP_013634961.1bHLH family protein
XP_013634977.1bHLH family protein
XP_013635081.1bHLH family protein
XP_013635096.1bHLH family protein
XP_013635294.1bHLH family protein
XP_013635306.1bHLH family protein
XP_013635599.1bHLH family protein
XP_013635790.1bHLH family protein
XP_013635791.1bHLH family protein
XP_013635792.1bHLH family protein
XP_013636159.1bHLH family protein
XP_013636160.1bHLH family protein
XP_013636341.1bHLH family protein
XP_013636451.1bHLH family protein
XP_013636652.1bHLH family protein
XP_013637009.1bHLH family protein
XP_013637084.1bHLH family protein
XP_013637414.1bHLH family protein
XP_013637415.1bHLH family protein
XP_013637526.1bHLH family protein
XP_013638209.1bHLH family protein
XP_013638323.1bHLH family protein
XP_013638439.1bHLH family protein
XP_013638454.1bHLH family protein
XP_013638496.1bHLH family protein
XP_013638509.1bHLH family protein
XP_013638510.1bHLH family protein
XP_013638511.1bHLH family protein
XP_013638512.1bHLH family protein
XP_013638513.1bHLH family protein
XP_013639182.1bHLH family protein
XP_013639210.1bHLH family protein
XP_013639300.1bHLH family protein
XP_013639306.1bHLH family protein
XP_013639567.1bHLH family protein
XP_013639574.1bHLH family protein
XP_013639692.1bHLH family protein
XP_013639696.1bHLH family protein
XP_013639731.1bHLH family protein
bHLH Family Introduction

The basic/helix-loop-helix (bHLH) proteins are a superfamily of transcription factors that have been well characterized in nonplant eukaryotes, especially in mammalian systems, in which considerable structural, functional, and phylogenetic analyses have been performed. The data indicate that bHLH proteins are important regulatory components in transcriptional networks in these systems, controlling a diversity of processes from cell proliferation to cell lineage establishment.

This family is defined by the bHLH signature domain, which consists of 60 amino acids with two functionally distinct regions. The basic region, located at the N-terminal end of the domain, is involved in DNA binding and consists of 15 amino acids with a high number of basic residues. The HLH region, at the C-terminal end, functions as a dimerization domain and is constituted mainly of hydrophobic residues that form two amphipathic -helices separated by a loop region of variable sequence and length. Outside of the conserved bHLH domain, these proteins exhibit considerable sequence divergence. Cocrystal structural analysis has shown that the interaction between the HLH regions of two separate polypeptides leads to the formation of homodimers and/or heterodimers and that the basic region of each partner binds to half of the DNA recognition sequence. Some bHLH proteins form homodimers or restrict their heterodimerization activity to closely related members of the family. On the other hand, some can form heterodimers with one or several different partners.

The core DNA sequence motif recognized by the bHLH proteins is a consensus hexanucleotide sequence known as the E-box (5'-CANNTG-3'). There are different types of E-boxes, depending on the identity of the two central bases. One of the most common is the palindromic G-box (5'-CACGTG-3'). Certain conserved amino acids within the basic region of the protein provide recognition of the core consensus site, whereas other residues in the domain dictate specificity for a given type of E-box . In addition, flanking nucleotides outside of the hexanucleotide core have been shown to play a role in binding specificity, and there is evidence that a loop residue in the protein plays a role in DNA binding through elements that lie outside of the core recognition sequence.

Toledo-Ortiz G, Huq E, Quail PH.
The Arabidopsis basic/helix-loop-helix transcription factor family.
Plant Cell. 2003 Aug;15(8):1749-70
PMID: 12897250