PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Brassica oleracea
E2F/DP Family
Species TF ID Description
XP_013583773.1E2F/DP family protein
XP_013587510.1E2F/DP family protein
XP_013602158.1E2F/DP family protein
XP_013602159.1E2F/DP family protein
XP_013604540.1E2F/DP family protein
XP_013608684.1E2F/DP family protein
XP_013608798.1E2F/DP family protein
XP_013609001.1E2F/DP family protein
XP_013618344.1E2F/DP family protein
XP_013618345.1E2F/DP family protein
XP_013618346.1E2F/DP family protein
XP_013618476.1E2F/DP family protein
XP_013618477.1E2F/DP family protein
XP_013622097.1E2F/DP family protein
XP_013625114.1E2F/DP family protein
XP_013625919.1E2F/DP family protein
XP_013631649.1E2F/DP family protein
XP_013631650.1E2F/DP family protein
XP_013631837.1E2F/DP family protein
E2F/DP Family Introduction

E2F transcription factors are a family of proteins that share a related DNA-binding domain and that bind to overlapping sets of target promoters. Most E2F proteins associate with a DP protein and form heterodimeric complexes that bind to DNA in a sequence-specific manner. E2F proteins control the temporal expression of genes that are needed for multiple processes during the cell cycle. Consequently, the level of E2F-dependent transcription is important for cell proliferation.

Different types of E2F complexes either activate or repress transcription. E2F repressor complexes suppress the transcription of their targets in quiescent cells, in differentiated cells and during the G1 phase of the cell cycle. When cells enter the cell cycle and proliferate, these repressors are disrupted and/or replaced by activator forms of E2F that promote gene expression.

van den Heuvel S, Dyson NJ.
Conserved functions of the pRB and E2F families.
Nat Rev Mol Cell Biol, 2008. 9(9): p. 713-24.
PMID: 18719710