PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Brassica napus
YABBY Family
Species TF ID Description
GSBRNA2T00018014001YABBY family protein
GSBRNA2T00019352001YABBY family protein
GSBRNA2T00025227001YABBY family protein
GSBRNA2T00033187001YABBY family protein
GSBRNA2T00037339001YABBY family protein
GSBRNA2T00037885001YABBY family protein
GSBRNA2T00037886001YABBY family protein
GSBRNA2T00047230001YABBY family protein
GSBRNA2T00061772001YABBY family protein
GSBRNA2T00066168001YABBY family protein
GSBRNA2T00079608001YABBY family protein
GSBRNA2T00082021001YABBY family protein
GSBRNA2T00100579001YABBY family protein
GSBRNA2T00101516001YABBY family protein
GSBRNA2T00101975001YABBY family protein
GSBRNA2T00104691001YABBY family protein
GSBRNA2T00105785001YABBY family protein
GSBRNA2T00119349001YABBY family protein
GSBRNA2T00122244001YABBY family protein
GSBRNA2T00138788001YABBY family protein
GSBRNA2T00138963001YABBY family protein
GSBRNA2T00156238001YABBY family protein
YABBY Family Introduction

Members of the YABBY gene family are characterized by two conserved domains, a C2C2 zinc finger-like domain towards the amino terminus and a helix-loop-helix, which we have called the YABBY domain, with sequence similarity to the first two helices of the HMG box towards the carboxyl end of the protein. In addition to the conserved YABBY and zinc finger domains, YAB1, YAB2, YAB3 and YAB5 display some sequence similarity on the carboxyl side of the YABBY domain. The region between the YABBY and zinc finger domains is variable amongst family members.

The presence of these domains suggests these proteins function as transcription factors. Database searches suggest that this family may be plant-specific, as genes with a similar arrangement of zinc finger and YABBY domains do not occur in either Caenorhabditis elegans or Saccharomyces cerevisiae.

The YABBY gene are expressed in a polar manner in all lateral organs produced by apical and flower meristems. Their transcripts are detectable only in the abaxial domains of lateral organs when their primordia emerge and begin to differentiate. Loss of polar expression of these genes results in loss of polar differentiation of cell types in lateral organs, and gain-of-function alleles result in abaxialization of lateral organs. The expression of these genes is precisely correlated with abaxial cell fate in mutants in which abaxial cell fates are found ectopically, reduced or eliminated. We propose that members of this gene family act redundantly to specify abaxial identity in lateral organs produced by the apical and flower meristems in Arabidopsis.

Siegfried KR, Eshed Y, Baum SF, Otsuga D, Drews GN, Bowman JL.
Members of the YABBY gene family specify abaxial cell fate in Arabidopsis.
Development. 1999 Sep;126(18):4117-28.
PMID: 10457020