PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Brassica napus
E2F/DP Family
Species TF ID Description
GSBRNA2T00000636001E2F/DP family protein
GSBRNA2T00002070001E2F/DP family protein
GSBRNA2T00017017001E2F/DP family protein
GSBRNA2T00023050001E2F/DP family protein
GSBRNA2T00032284001E2F/DP family protein
GSBRNA2T00032375001E2F/DP family protein
GSBRNA2T00049278001E2F/DP family protein
GSBRNA2T00057732001E2F/DP family protein
GSBRNA2T00063031001E2F/DP family protein
GSBRNA2T00064149001E2F/DP family protein
GSBRNA2T00069548001E2F/DP family protein
GSBRNA2T00076558001E2F/DP family protein
GSBRNA2T00077252001E2F/DP family protein
GSBRNA2T00080030001E2F/DP family protein
GSBRNA2T00081161001E2F/DP family protein
GSBRNA2T00087787001E2F/DP family protein
GSBRNA2T00092264001E2F/DP family protein
GSBRNA2T00092788001E2F/DP family protein
GSBRNA2T00094943001E2F/DP family protein
GSBRNA2T00106268001E2F/DP family protein
GSBRNA2T00117117001E2F/DP family protein
GSBRNA2T00132443001E2F/DP family protein
GSBRNA2T00134217001E2F/DP family protein
GSBRNA2T00134264001E2F/DP family protein
GSBRNA2T00136462001E2F/DP family protein
GSBRNA2T00140919001E2F/DP family protein
GSBRNA2T00141197001E2F/DP family protein
GSBRNA2T00141838001E2F/DP family protein
GSBRNA2T00143293001E2F/DP family protein
GSBRNA2T00148871001E2F/DP family protein
GSBRNA2T00151773001E2F/DP family protein
GSBRNA2T00154124001E2F/DP family protein
E2F/DP Family Introduction

E2F transcription factors are a family of proteins that share a related DNA-binding domain and that bind to overlapping sets of target promoters. Most E2F proteins associate with a DP protein and form heterodimeric complexes that bind to DNA in a sequence-specific manner. E2F proteins control the temporal expression of genes that are needed for multiple processes during the cell cycle. Consequently, the level of E2F-dependent transcription is important for cell proliferation.

Different types of E2F complexes either activate or repress transcription. E2F repressor complexes suppress the transcription of their targets in quiescent cells, in differentiated cells and during the G1 phase of the cell cycle. When cells enter the cell cycle and proliferate, these repressors are disrupted and/or replaced by activator forms of E2F that promote gene expression.

van den Heuvel S, Dyson NJ.
Conserved functions of the pRB and E2F families.
Nat Rev Mol Cell Biol, 2008. 9(9): p. 713-24.
PMID: 18719710