PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Brachypodium distachyon
bHLH Family
Species TF ID Description
Bradi1g04280.2.pbHLH family protein
Bradi1g04280.3.pbHLH family protein
Bradi1g05037.1.pbHLH family protein
Bradi1g05037.2.pbHLH family protein
Bradi1g05430.1.pbHLH family protein
Bradi1g05430.3.pbHLH family protein
Bradi1g06670.1.pbHLH family protein
Bradi1g07936.1.pbHLH family protein
Bradi1g09177.1.pbHLH family protein
Bradi1g09960.1.pbHLH family protein
Bradi1g09960.2.pbHLH family protein
Bradi1g09960.3.pbHLH family protein
Bradi1g09960.4.pbHLH family protein
Bradi1g09960.5.pbHLH family protein
Bradi1g09960.6.pbHLH family protein
Bradi1g10170.2.pbHLH family protein
Bradi1g10170.3.pbHLH family protein
Bradi1g10170.4.pbHLH family protein
Bradi1g12760.2.pbHLH family protein
Bradi1g12770.2.pbHLH family protein
Bradi1g12780.4.pbHLH family protein
Bradi1g13980.2.pbHLH family protein
Bradi1g14600.1.pbHLH family protein
Bradi1g18400.1.pbHLH family protein
Bradi1g22960.1.pbHLH family protein
Bradi1g25230.1.pbHLH family protein
Bradi1g25230.2.pbHLH family protein
Bradi1g25470.1.pbHLH family protein
Bradi1g30000.1.pbHLH family protein
Bradi1g30000.2.pbHLH family protein
Bradi1g35990.1.pbHLH family protein
Bradi1g35990.2.pbHLH family protein
Bradi1g37540.2.pbHLH family protein
Bradi1g38650.1.pbHLH family protein
Bradi1g42440.1.pbHLH family protein
Bradi1g43650.1.pbHLH family protein
Bradi1g43650.2.pbHLH family protein
Bradi1g45260.1.pbHLH family protein
Bradi1g46100.1.pbHLH family protein
Bradi1g46700.1.pbHLH family protein
Bradi1g46700.2.pbHLH family protein
Bradi1g47350.1.pbHLH family protein
Bradi1g48400.1.pbHLH family protein
Bradi1g48400.2.pbHLH family protein
Bradi1g54070.1.pbHLH family protein
Bradi1g54111.3.pbHLH family protein
Bradi1g54111.4.pbHLH family protein
Bradi1g54690.1.pbHLH family protein
Bradi1g54690.2.pbHLH family protein
Bradi1g54690.3.pbHLH family protein
Bradi1g54690.4.pbHLH family protein
Bradi1g55427.1.pbHLH family protein
Bradi1g55427.2.pbHLH family protein
Bradi1g55427.3.pbHLH family protein
Bradi1g58230.1.pbHLH family protein
Bradi1g61110.1.pbHLH family protein
Bradi1g61110.2.pbHLH family protein
Bradi1g66345.2.pbHLH family protein
Bradi1g67500.1.pbHLH family protein
Bradi1g69110.2.pbHLH family protein
Bradi1g69110.3.pbHLH family protein
Bradi1g69110.4.pbHLH family protein
Bradi1g69110.5.pbHLH family protein
Bradi1g69197.1.pbHLH family protein
Bradi1g70860.1.pbHLH family protein
Bradi1g71990.2.pbHLH family protein
Bradi1g73140.1.pbHLH family protein
Bradi1g73161.1.pbHLH family protein
Bradi1g76030.1.pbHLH family protein
Bradi1g76440.1.pbHLH family protein
Bradi1g77070.1.pbHLH family protein
Bradi2g00720.1.pbHLH family protein
Bradi2g00730.1.pbHLH family protein
Bradi2g00740.1.pbHLH family protein
Bradi2g01000.1.pbHLH family protein
Bradi2g01000.2.pbHLH family protein
Bradi2g03427.1.pbHLH family protein
Bradi2g03427.2.pbHLH family protein
Bradi2g03427.3.pbHLH family protein
Bradi2g03830.2.pbHLH family protein
Bradi2g03830.3.pbHLH family protein
Bradi2g03830.4.pbHLH family protein
Bradi2g05950.2.pbHLH family protein
Bradi2g07050.1.pbHLH family protein
Bradi2g08080.1.pbHLH family protein
Bradi2g08080.2.pbHLH family protein
Bradi2g11100.1.pbHLH family protein
Bradi2g11100.2.pbHLH family protein
Bradi2g11260.1.pbHLH family protein
Bradi2g12490.1.pbHLH family protein
Bradi2g18200.1.pbHLH family protein
Bradi2g20720.2.pbHLH family protein
Bradi2g20720.3.pbHLH family protein
Bradi2g20720.4.pbHLH family protein
Bradi2g22810.1.pbHLH family protein
Bradi2g23520.1.pbHLH family protein
Bradi2g34600.1.pbHLH family protein
Bradi2g36740.1.pbHLH family protein
Bradi2g39970.1.pbHLH family protein
Bradi2g41390.1.pbHLH family protein
Bradi2g41670.1.pbHLH family protein
Bradi2g44117.10.pbHLH family protein
Bradi2g44117.1.pbHLH family protein
Bradi2g44117.2.pbHLH family protein
Bradi2g44117.4.pbHLH family protein
Bradi2g44117.6.pbHLH family protein
Bradi2g44117.7.pbHLH family protein
Bradi2g44117.8.pbHLH family protein
Bradi2g44117.9.pbHLH family protein
Bradi2g47730.1.pbHLH family protein
Bradi2g47810.1.pbHLH family protein
Bradi2g51990.1.pbHLH family protein
Bradi2g51990.3.pbHLH family protein
Bradi2g54030.1.pbHLH family protein
Bradi2g57800.1.pbHLH family protein
Bradi2g57800.2.pbHLH family protein
Bradi2g57800.3.pbHLH family protein
Bradi2g57800.4.pbHLH family protein
Bradi2g57800.5.pbHLH family protein
Bradi2g57800.6.pbHLH family protein
Bradi2g57800.7.pbHLH family protein
Bradi2g58630.2.pbHLH family protein
Bradi2g59497.2.pbHLH family protein
Bradi2g60970.1.pbHLH family protein
Bradi2g60970.2.pbHLH family protein
Bradi2g61050.1.pbHLH family protein
Bradi2g61050.2.pbHLH family protein
Bradi3g01540.1.pbHLH family protein
Bradi3g01901.3.pbHLH family protein
Bradi3g01901.4.pbHLH family protein
Bradi3g01901.5.pbHLH family protein
Bradi3g01901.6.pbHLH family protein
Bradi3g01901.7.pbHLH family protein
Bradi3g01910.1.pbHLH family protein
Bradi3g01910.2.pbHLH family protein
Bradi3g08280.1.pbHLH family protein
Bradi3g08810.1.pbHLH family protein
Bradi3g09670.1.pbHLH family protein
Bradi3g11520.1.pbHLH family protein
Bradi3g13300.1.pbHLH family protein
Bradi3g14590.1.pbHLH family protein
Bradi3g15440.1.pbHLH family protein
Bradi3g21460.10.pbHLH family protein
Bradi3g21460.11.pbHLH family protein
Bradi3g21460.12.pbHLH family protein
Bradi3g21460.13.pbHLH family protein
Bradi3g21460.1.pbHLH family protein
Bradi3g21460.2.pbHLH family protein
Bradi3g21460.5.pbHLH family protein
Bradi3g21460.7.pbHLH family protein
Bradi3g21460.8.pbHLH family protein
Bradi3g21460.9.pbHLH family protein
Bradi3g33170.2.pbHLH family protein
Bradi3g33170.3.pbHLH family protein
Bradi3g33170.4.pbHLH family protein
Bradi3g33170.5.pbHLH family protein
Bradi3g34200.1.pbHLH family protein
Bradi3g36610.1.pbHLH family protein
Bradi3g38250.1.pbHLH family protein
Bradi3g38360.1.pbHLH family protein
Bradi3g38510.1.pbHLH family protein
Bradi3g38890.1.pbHLH family protein
Bradi3g38970.1.pbHLH family protein
Bradi3g38970.3.pbHLH family protein
Bradi3g38970.4.pbHLH family protein
Bradi3g38970.5.pbHLH family protein
Bradi3g39927.1.pbHLH family protein
Bradi3g40860.1.pbHLH family protein
Bradi3g40860.2.pbHLH family protein
Bradi3g41510.1.pbHLH family protein
Bradi3g41510.2.pbHLH family protein
Bradi3g41930.1.pbHLH family protein
Bradi3g41940.1.pbHLH family protein
Bradi3g41950.1.pbHLH family protein
Bradi3g43250.3.pbHLH family protein
Bradi3g45360.2.pbHLH family protein
Bradi3g45360.3.pbHLH family protein
Bradi3g45360.4.pbHLH family protein
Bradi3g45365.1.pbHLH family protein
Bradi3g45370.2.pbHLH family protein
Bradi3g46200.1.pbHLH family protein
Bradi3g46200.2.pbHLH family protein
Bradi3g48070.3.pbHLH family protein
Bradi3g48070.4.pbHLH family protein
Bradi3g52150.1.pbHLH family protein
Bradi3g52790.1.pbHLH family protein
Bradi3g52790.2.pbHLH family protein
Bradi3g53060.2.pbHLH family protein
Bradi3g54070.1.pbHLH family protein
Bradi3g54640.1.pbHLH family protein
Bradi3g54640.2.pbHLH family protein
Bradi3g54640.3.pbHLH family protein
Bradi3g56340.1.pbHLH family protein
Bradi3g56340.2.pbHLH family protein
Bradi3g58360.1.pbHLH family protein
Bradi3g59290.1.pbHLH family protein
Bradi4g00920.2.pbHLH family protein
Bradi4g00920.3.pbHLH family protein
Bradi4g02665.1.pbHLH family protein
Bradi4g02670.2.pbHLH family protein
Bradi4g02673.1.pbHLH family protein
Bradi4g03070.1.pbHLH family protein
Bradi4g03070.2.pbHLH family protein
Bradi4g06567.3.pbHLH family protein
Bradi4g12615.1.pbHLH family protein
Bradi4g14190.1.pbHLH family protein
Bradi4g14190.5.pbHLH family protein
Bradi4g17460.1.pbHLH family protein
Bradi4g17460.2.pbHLH family protein
Bradi4g19577.2.pbHLH family protein
Bradi4g28800.2.pbHLH family protein
Bradi4g29370.1.pbHLH family protein
Bradi4g29990.1.pbHLH family protein
Bradi4g30350.1.pbHLH family protein
Bradi4g30350.2.pbHLH family protein
Bradi4g30350.3.pbHLH family protein
Bradi4g30350.4.pbHLH family protein
Bradi4g30350.5.pbHLH family protein
Bradi4g30350.6.pbHLH family protein
Bradi4g30350.7.pbHLH family protein
Bradi4g30350.8.pbHLH family protein
Bradi4g32060.1.pbHLH family protein
Bradi4g32470.1.pbHLH family protein
Bradi4g32650.1.pbHLH family protein
Bradi4g32650.2.pbHLH family protein
Bradi4g32934.1.pbHLH family protein
Bradi4g32967.2.pbHLH family protein
Bradi4g33670.1.pbHLH family protein
Bradi4g34350.1.pbHLH family protein
Bradi4g34870.1.pbHLH family protein
Bradi4g34870.3.pbHLH family protein
Bradi4g34870.4.pbHLH family protein
Bradi4g34870.5.pbHLH family protein
Bradi4g34870.6.pbHLH family protein
Bradi4g34870.7.pbHLH family protein
Bradi4g35400.1.pbHLH family protein
Bradi5g01900.1.pbHLH family protein
Bradi5g05110.1.pbHLH family protein
Bradi5g05110.2.pbHLH family protein
Bradi5g06620.1.pbHLH family protein
Bradi5g07720.1.pbHLH family protein
Bradi5g19950.1.pbHLH family protein
Bradi5g20397.2.pbHLH family protein
Bradi5g20397.3.pbHLH family protein
Bradi5g21950.1.pbHLH family protein
Bradi5g22920.1.pbHLH family protein
Bradi5g23580.1.pbHLH family protein
bHLH Family Introduction

The basic/helix-loop-helix (bHLH) proteins are a superfamily of transcription factors that have been well characterized in nonplant eukaryotes, especially in mammalian systems, in which considerable structural, functional, and phylogenetic analyses have been performed. The data indicate that bHLH proteins are important regulatory components in transcriptional networks in these systems, controlling a diversity of processes from cell proliferation to cell lineage establishment.

This family is defined by the bHLH signature domain, which consists of 60 amino acids with two functionally distinct regions. The basic region, located at the N-terminal end of the domain, is involved in DNA binding and consists of 15 amino acids with a high number of basic residues. The HLH region, at the C-terminal end, functions as a dimerization domain and is constituted mainly of hydrophobic residues that form two amphipathic -helices separated by a loop region of variable sequence and length. Outside of the conserved bHLH domain, these proteins exhibit considerable sequence divergence. Cocrystal structural analysis has shown that the interaction between the HLH regions of two separate polypeptides leads to the formation of homodimers and/or heterodimers and that the basic region of each partner binds to half of the DNA recognition sequence. Some bHLH proteins form homodimers or restrict their heterodimerization activity to closely related members of the family. On the other hand, some can form heterodimers with one or several different partners.

The core DNA sequence motif recognized by the bHLH proteins is a consensus hexanucleotide sequence known as the E-box (5'-CANNTG-3'). There are different types of E-boxes, depending on the identity of the two central bases. One of the most common is the palindromic G-box (5'-CACGTG-3'). Certain conserved amino acids within the basic region of the protein provide recognition of the core consensus site, whereas other residues in the domain dictate specificity for a given type of E-box . In addition, flanking nucleotides outside of the hexanucleotide core have been shown to play a role in binding specificity, and there is evidence that a loop residue in the protein plays a role in DNA binding through elements that lie outside of the core recognition sequence.

Toledo-Ortiz G, Huq E, Quail PH.
The Arabidopsis basic/helix-loop-helix transcription factor family.
Plant Cell. 2003 Aug;15(8):1749-70
PMID: 12897250