PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Arabidopsis thaliana
WRKY Family
Species TF ID Description
AT1G13960.1WRKY DNA-binding protein 4
AT1G13960.2WRKY DNA-binding protein 4
AT1G18860.1WRKY DNA-binding protein 61
AT1G29280.1WRKY DNA-binding protein 65
AT1G29860.1WRKY DNA-binding protein 71
AT1G30650.1WRKY DNA-binding protein 14
AT1G55600.1WRKY DNA-binding protein 10
AT1G62300.1WRKY family protein
AT1G64000.1WRKY DNA-binding protein 56
AT1G66550.1WRKY DNA-binding protein 67
AT1G66550.2WRKY DNA-binding protein 67
AT1G66560.1WRKY DNA-binding protein 64
AT1G66600.1ABA overly sensitive mutant 3
AT1G68150.1WRKY DNA-binding protein 9
AT1G69310.1WRKY DNA-binding protein 57
AT1G69310.2WRKY DNA-binding protein 57
AT1G69810.1WRKY DNA-binding protein 36
AT1G80590.1WRKY DNA-binding protein 66
AT1G80840.1WRKY DNA-binding protein 40
AT2G03340.1WRKY DNA-binding protein 3
AT2G04880.1zinc-dependent activator protein-1
AT2G04880.2zinc-dependent activator protein-1
AT2G21900.1WRKY DNA-binding protein 59
AT2G23320.1WRKY DNA-binding protein 15
AT2G23320.2WRKY DNA-binding protein 15
AT2G24570.1WRKY DNA-binding protein 17
AT2G25000.1WRKY DNA-binding protein 60
AT2G30250.1WRKY DNA-binding protein 25
AT2G30590.1WRKY DNA-binding protein 21
AT2G34830.1WRKY DNA-binding protein 35
AT2G37260.1WRKY family protein
AT2G37260.2WRKY family protein
AT2G38470.1WRKY DNA-binding protein 33
AT2G40740.1WRKY DNA-binding protein 55
AT2G40740.2WRKY DNA-binding protein 55
AT2G40750.1WRKY DNA-binding protein 54
AT2G44745.1WRKY family protein
AT2G46130.1WRKY DNA-binding protein 43
AT2G46130.2WRKY DNA-binding protein 43
AT2G46400.1WRKY DNA-binding protein 46
AT2G47260.1WRKY DNA-binding protein 23
AT3G01080.1WRKY DNA-binding protein 58
AT3G01970.1WRKY DNA-binding protein 45
AT3G04670.1WRKY DNA-binding protein 39
AT3G04670.2WRKY DNA-binding protein 39
AT3G56400.1WRKY DNA-binding protein 70
AT3G58710.1WRKY DNA-binding protein 69
AT3G58710.2WRKY DNA-binding protein 69
AT3G62340.1WRKY family protein
AT4G01250.1WRKY family protein
AT4G01720.1WRKY family protein
AT4G04450.1WRKY family protein
AT4G11070.1WRKY family protein
AT4G11070.2WRKY family protein
AT4G12020.1WRKY family protein
AT4G12020.2WRKY family protein
AT4G12020.3WRKY family protein
AT4G18170.1WRKY DNA-binding protein 28
AT4G22070.1WRKY DNA-binding protein 31
AT4G23550.1WRKY family protein
AT4G23810.1WRKY family protein
AT4G24240.1WRKY DNA-binding protein 7
AT4G26440.1WRKY DNA-binding protein 34
AT4G26640.1WRKY family protein
AT4G26640.2WRKY family protein
AT4G30935.1WRKY DNA-binding protein 32
AT4G31550.1WRKY DNA-binding protein 11
AT4G31550.2WRKY DNA-binding protein 11
AT4G31800.1WRKY DNA-binding protein 18
AT4G31800.2WRKY DNA-binding protein 18
AT4G39410.1WRKY DNA-binding protein 13
AT5G01900.1WRKY DNA-binding protein 62
AT5G07100.1WRKY DNA-binding protein 26
AT5G07100.2WRKY DNA-binding protein 26
AT5G13080.1WRKY DNA-binding protein 75
AT5G15130.1WRKY DNA-binding protein 72
AT5G22570.1WRKY DNA-binding protein 38
AT5G24110.1WRKY DNA-binding protein 30
AT5G26170.1WRKY DNA-binding protein 50
AT5G28650.1WRKY DNA-binding protein 74
AT5G41570.1WRKY DNA-binding protein 24
AT5G43290.1WRKY DNA-binding protein 49
AT5G45050.1Disease resistance protein (TIR-NBS-LRR class)
AT5G45050.2Disease resistance protein (TIR-NBS-LRR class)
AT5G45260.1Disease resistance protein (TIR-NBS-LRR class)
AT5G46350.1WRKY DNA-binding protein 8
AT5G49520.1WRKY DNA-binding protein 48
AT5G52830.1WRKY DNA-binding protein 27
AT5G56270.1WRKY DNA-binding protein 2
AT5G64810.1WRKY DNA-binding protein 51
WRKY Family Introduction

WRKY transcription factors are one of the largest families of transcriptional regulators in plants and form integral parts of signalling webs that modulate many plant processes. Here, we review recent significant progress in WRKY transcription factor research. New findings illustrate that WRKY proteins often act as repressors as well as activators, and that members of the family play roles in both the repression and de-repression of important plant processes. Furthermore, it is becoming clear that a single WRKY transcription factor might be involved in regulating several seemingly disparate processes. Mechanisms of signalling and transcriptional regulation are being dissected, uncovering WRKY protein functions via interactions with a diverse array of protein partners, including MAP kinases, MAP kinase kinases, 14-3-3 proteins, calmodulin, histone deacetylases, resistance proteins and other WRKY transcription factors. WRKY genes exhibit extensive autoregulation and cross-regulation that facilitates transcriptional reprogramming in a dynamic web with built-in redundancy.

The defining feature of WRKY transcription factors is their DNA binding domain. This is called the WRKY domain after the almost invariant WRKY amino acid sequence at the N-terminus. In a few WRKY proteins, the WRKY amino acid sequences have been replaced by WRRY, WSKY, WKRY, WVKY or WKKY. The WRKY domain is about 60 residues in length, and as well as containing the WRKY signature it also has an atypical zinc-finger structure at the C-terminus. The zinc-finger structure is either Cx4-5Cx22-23HxH or Cx7Cx23HxC. Initially, in the absence of a complete gene family from any plant species, the WRKY transcription factors were divided into three groups based on the number of WRKY domains (two domains in Group I proteins and one in the others) and the structure of their zinc fingers (C2HC in Group III proteins).

Rushton PJ, Somssich IE, Ringler P, Shen QJ.
WRKY transcription factors.
Trends Plant Sci, 2010. 15(5): p. 247-58.
PMID: 20304701