Plant Transcription
Factor Database
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Species  TF ID  Description 

AT1G09030.1  nuclear factor Y, subunit B4  
AT1G21970.1  NFYB family protein  
AT2G13570.1  nuclear factor Y, subunit B7  
AT2G27470.1  nuclear factor Y, subunit B11  
AT2G37060.1  nuclear factor Y, subunit B8  
AT2G37060.2  nuclear factor Y, subunit B8  
AT2G37060.3  nuclear factor Y, subunit B8  
AT2G38880.1  nuclear factor Y, subunit B1  
AT2G38880.2  nuclear factor Y, subunit B1  
AT2G38880.3  nuclear factor Y, subunit B1  
AT2G38880.4  nuclear factor Y, subunit B1  
AT2G38880.5  nuclear factor Y, subunit B1  
AT2G38880.6  nuclear factor Y, subunit B1  
AT2G38880.7  nuclear factor Y, subunit B1  
AT2G38880.8  nuclear factor Y, subunit B1  
AT2G47810.1  nuclear factor Y, subunit B5  
AT3G53340.1  nuclear factor Y, subunit B10  
AT4G14540.1  nuclear factor Y, subunit B3  
AT5G08190.1  nuclear factor Y, subunit B12  
AT5G08190.2  nuclear factor Y, subunit B12  
AT5G23090.1  nuclear factor Y, subunit B13  
AT5G23090.2  nuclear factor Y, subunit B13  
AT5G23090.3  nuclear factor Y, subunit B13  
AT5G23090.4  nuclear factor Y, subunit B13  
AT5G47640.1  nuclear factor Y, subunit B2  
AT5G47670.1  nuclear factor Y, subunit B6  
AT5G47670.2  nuclear factor Y, subunit B6 
NFY transcription factors are likely found in all eukaryotes and have roles in the regulation of diverse genes (McNabb et al., 1995; Edwards et al., 1998; Maity and de Crombrugghe, 1998; Mantovani, 1999). In mammals, where their biochemistry is well described, the NFY transcription factor complex is composed of three unique subunits: NFYA, NFYB, and NFYC. Assembly of the NFY heterotrimer in mammals follows a strict, stepwise pattern (Sinha et al., 1995, 1996). Initially, a heterodimer is formed in the cytoplasm between the subunits NFYB and NFYC. This dimer then translocates to the nucleus, where the third subunit, NFYA, is recruited to generate the mature, heterotrimeric NFY transcription factor (Frontini et al., 2004; Kahle et al., 2005). Mature NFY binds promoters with the core pentamer nucleotide sequence CCAAT, and this can result in either positive or negative transcriptional regulation(Peng and Jahroudi, 2002, 2003; Ceribelli et al., 2008).
As with NFYA, NFYB and NFYC families have welldescribed subunit interaction and DNAbinding domains ( Kim et al., 1996; Sinha et al., 1996; McNabb et al., 1997; Romier et al., 2003). The conserved regions of NFYB and NFYC have structural and amino acid homology to histone fold motifs. Specifically, NFYB is related to the histone fold motifs of H2B histones, while NFYC subunits are related to H2A histones (Mantovani, 1999).
Siefers N, Dang KK, Kumimoto RW, Bynum WE 4th, Tayrose G, Holt BF 3rd.
Tissuespecific expression patterns of Arabidopsis NFY transcription factors suggest potential for extensive combinatorial complexity.
Plant Physiol, 2009. 149(2): p. 62541.
PMID: 19019982