PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Arabidopsis thaliana
BES1 Family
Species TF ID Description
AT1G19350.1BES1 family protein
AT1G19350.3BES1 family protein
AT1G19350.4BES1 family protein
AT1G19350.5BES1 family protein
AT1G19350.6BES1 family protein
AT1G75080.1BES1 family protein
AT1G75080.2BES1 family protein
AT1G78700.1BES1/BZR1 homolog 4
AT2G45880.1beta-amylase 7
AT3G50750.1BES1/BZR1 homolog 1
AT4G18890.1BES1/BZR1 homolog 3
AT4G36780.1BES1/BZR1 homolog 2
AT5G45300.1beta-amylase 2
AT5G45300.2beta-amylase 2
BES1 Family Introduction

Brassinosteroids (BRs) signal through a plasma membrane-localized receptor kinase to regulate plant growth and development. We showed previously that a novel protein, BES1(BRI1-EMS-SUPPRESSOR 1), accumulates in the nucleus in response to BRs, where it plays a role in BR-regulated gene expression; however, the mechanism by which BES1 regulates gene expression is unknown. In this study, we dissect BES1 subdomains and establish that BES1 is a transcription factor that binds to and activates BR target gene promoters both in vitro and in vivo. BES1 interacts with a basic helix-loop-helix protein, BIM1, to synergistically bind to E box (CANNTG) sequences present in many BR-induced promoters. Loss-of-function and gain-of-function mutants of BIM1 and its close family members display BR response phenotypes. Thus, BES1 defines a new class of plant-specific transcription factors that cooperate with transcription factors such as BIM1 to regulate BR-induced genes.

Yin Y, Vafeados D, Tao Y, Yoshida S, Asami T, Chory J.
A new class of transcription factors mediates brassinosteroid-regulated gene expression in Arabidopsis.
Cell. 2005 Jan 28;120(2):249-59.
PMID: 15680330