Plant Transcription Factor Database
Previous version: v1.0, v2.0, v3.0
Arabidopsis thaliana
ARF Family
Species TF ID Description
AT1G19220.1auxin response factor 19
AT1G19850.1ARF family protein
AT1G30330.1auxin response factor 6
AT1G30330.2auxin response factor 6
AT1G34310.1auxin response factor 12
AT1G34390.1auxin response factor 22
AT1G34410.1auxin response factor 21
AT1G35240.1auxin response factor 20
AT1G35520.1auxin response factor 15
AT1G35540.1auxin response factor 14
AT1G59750.1auxin response factor 1
AT1G59750.2auxin response factor 1
AT1G59750.3auxin response factor 1
AT1G59750.4auxin response factor 1
AT1G77850.1auxin response factor 17
AT2G28350.1auxin response factor 10
AT2G33860.1ARF family protein
AT2G46530.1auxin response factor 11
AT2G46530.2auxin response factor 11
AT2G46530.3auxin response factor 11
AT3G61830.1auxin response factor 18
AT4G23980.1auxin response factor 9
AT4G23980.2auxin response factor 9
AT4G30080.1auxin response factor 16
AT5G20730.1ARF family protein
AT5G20730.2ARF family protein
AT5G20730.3ARF family protein
AT5G37020.1auxin response factor 8
AT5G37020.2auxin response factor 8
AT5G60450.1auxin response factor 4
AT5G62000.1auxin response factor 2
AT5G62000.2auxin response factor 2
AT5G62000.3auxin response factor 2
AT5G62000.4auxin response factor 2
ARF Family Introduction

Auxin response factors (ARF) are transcription factors that regulate the expression of auxin response genes. ARFs bind with specificity to TGTCTC auxin response elements (AuxRE) in promoters of these genes and function in combination with Aux/IAA (auxin/indole acetic acid) repressors, which dimerize with ARF activators in an auxin-regulated manner.

Most ARFs consist of an amino-terminal DNA-binding domain (DBD), a middle region that functions as an activation domain (AD) or repression domain (RD), and a carboxy-terminal dimerization domain (CTD). The ARF DBD is classified as a plant-specific B3-type, but requires additional amino-terminal and carboxy-terminal amino acids for efficient in vitro binding to TGTCTC AuxREs.

The ARF ADs and RDs are located just carboxy-terminal to the DBDs and contain biased amino acid sequences. ARF ADs are enriched in glutamine along with serine and leucine residues, while ARF RDs are enriched in serine, proline, leucine and glycine residues.

Guilfoyle TJ, Hagen G.
Auxin response factors.
Curr Opin Plant Biol, 2007. 10(5): p. 453-60.
PMID: 17900969