PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Aegilops tauschii
WRKY Family
Species TF ID Description
EMT00560WRKY family protein
EMT00562WRKY family protein
EMT00743WRKY family protein
EMT00875WRKY family protein
EMT01449WRKY family protein
EMT01578WRKY family protein
EMT03342WRKY family protein
EMT03756WRKY family protein
EMT04396WRKY family protein
EMT05704WRKY family protein
EMT06925WRKY family protein
EMT07733WRKY family protein
EMT08499WRKY family protein
EMT08686WRKY family protein
EMT09005WRKY family protein
EMT10148WRKY family protein
EMT10166WRKY family protein
EMT10371WRKY family protein
EMT10372WRKY family protein
EMT11324WRKY family protein
EMT12694WRKY family protein
EMT13369WRKY family protein
EMT13570WRKY family protein
EMT13814WRKY family protein
EMT14404WRKY family protein
EMT14792WRKY family protein
EMT15033WRKY family protein
EMT15265WRKY family protein
EMT15410WRKY family protein
EMT15914WRKY family protein
EMT16145WRKY family protein
EMT16363WRKY family protein
EMT16364WRKY family protein
EMT16491WRKY family protein
EMT16619WRKY family protein
EMT16727WRKY family protein
EMT17791WRKY family protein
EMT17792WRKY family protein
EMT18192WRKY family protein
EMT18262WRKY family protein
EMT18619WRKY family protein
EMT18620WRKY family protein
EMT18621WRKY family protein
EMT19032WRKY family protein
EMT19399WRKY family protein
EMT19877WRKY family protein
EMT19878WRKY family protein
EMT20201WRKY family protein
EMT21015WRKY family protein
EMT21028WRKY family protein
EMT21213WRKY family protein
EMT21551WRKY family protein
EMT21586WRKY family protein
EMT21861WRKY family protein
EMT21988WRKY family protein
EMT21991WRKY family protein
EMT22054WRKY family protein
EMT22420WRKY family protein
EMT22421WRKY family protein
EMT22515WRKY family protein
EMT22592WRKY family protein
EMT22670WRKY family protein
EMT24994WRKY family protein
EMT25163WRKY family protein
EMT25252WRKY family protein
EMT25430WRKY family protein
EMT25875WRKY family protein
EMT26167WRKY family protein
EMT26633WRKY family protein
EMT27315WRKY family protein
EMT27386WRKY family protein
EMT27471WRKY family protein
EMT28664WRKY family protein
EMT28936WRKY family protein
EMT29146WRKY family protein
EMT29174WRKY family protein
EMT29238WRKY family protein
EMT29367WRKY family protein
EMT29414WRKY family protein
EMT29513WRKY family protein
EMT29685WRKY family protein
EMT29741WRKY family protein
EMT31413WRKY family protein
EMT31776WRKY family protein
EMT31777WRKY family protein
EMT31778WRKY family protein
EMT31937WRKY family protein
EMT32446WRKY family protein
EMT33035WRKY family protein
EMT33135WRKY family protein
EMT33502WRKY family protein
EMT33560WRKY family protein
WRKY Family Introduction

WRKY transcription factors are one of the largest families of transcriptional regulators in plants and form integral parts of signalling webs that modulate many plant processes. Here, we review recent significant progress in WRKY transcription factor research. New findings illustrate that WRKY proteins often act as repressors as well as activators, and that members of the family play roles in both the repression and de-repression of important plant processes. Furthermore, it is becoming clear that a single WRKY transcription factor might be involved in regulating several seemingly disparate processes. Mechanisms of signalling and transcriptional regulation are being dissected, uncovering WRKY protein functions via interactions with a diverse array of protein partners, including MAP kinases, MAP kinase kinases, 14-3-3 proteins, calmodulin, histone deacetylases, resistance proteins and other WRKY transcription factors. WRKY genes exhibit extensive autoregulation and cross-regulation that facilitates transcriptional reprogramming in a dynamic web with built-in redundancy.

The defining feature of WRKY transcription factors is their DNA binding domain. This is called the WRKY domain after the almost invariant WRKY amino acid sequence at the N-terminus. In a few WRKY proteins, the WRKY amino acid sequences have been replaced by WRRY, WSKY, WKRY, WVKY or WKKY. The WRKY domain is about 60 residues in length, and as well as containing the WRKY signature it also has an atypical zinc-finger structure at the C-terminus. The zinc-finger structure is either Cx4-5Cx22-23HxH or Cx7Cx23HxC. Initially, in the absence of a complete gene family from any plant species, the WRKY transcription factors were divided into three groups based on the number of WRKY domains (two domains in Group I proteins and one in the others) and the structure of their zinc fingers (C2HC in Group III proteins).

Rushton PJ, Somssich IE, Ringler P, Shen QJ.
WRKY transcription factors.
Trends Plant Sci, 2010. 15(5): p. 247-58.
PMID: 20304701