PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Arabidopsis lyrata
bZIP Family
Species TF ID Description
311885bZIP family protein
312884bZIP family protein
321332bZIP family protein
322281bZIP family protein
324178bZIP family protein
342995bZIP family protein
343397bZIP family protein
470374bZIP family protein
472441bZIP family protein
473396bZIP family protein
473749bZIP family protein
473775bZIP family protein
473850bZIP family protein
474101bZIP family protein
475358bZIP family protein
475990bZIP family protein
476015bZIP family protein
478415bZIP family protein
478587bZIP family protein
479237bZIP family protein
479444bZIP family protein
480043bZIP family protein
480722bZIP family protein
480978bZIP family protein
482066bZIP family protein
482512bZIP family protein
483119bZIP family protein
483175bZIP family protein
483330bZIP family protein
484308bZIP family protein
484862bZIP family protein
485555bZIP family protein
486262bZIP family protein
486343bZIP family protein
486748bZIP family protein
487498bZIP family protein
487510bZIP family protein
487514bZIP family protein
487538bZIP family protein
487648bZIP family protein
487829bZIP family protein
488428bZIP family protein
489663bZIP family protein
490295bZIP family protein
491198bZIP family protein
491272bZIP family protein
494588bZIP family protein
495000bZIP family protein
496230bZIP family protein
856577bZIP family protein
856771bZIP family protein
856954bZIP family protein
857922bZIP family protein
864390bZIP family protein
876088bZIP family protein
877903bZIP family protein
878856bZIP family protein
884485bZIP family protein
886806bZIP family protein
887800bZIP family protein
888726bZIP family protein
892661bZIP family protein
895409bZIP family protein
899560bZIP family protein
900000bZIP family protein
900536bZIP family protein
900741bZIP family protein
903398bZIP family protein
905328bZIP family protein
906289bZIP family protein
906872bZIP family protein
907132bZIP family protein
909087bZIP family protein
910526bZIP family protein
912691bZIP family protein
912881bZIP family protein
916437bZIP family protein
919930bZIP family protein
920430bZIP family protein
920531bZIP family protein
bZIP Family Introduction

The bZIP domain consists of two structural features located on a contiguous alpha-helix: first, a basic region of ~ 16 amino acid residues containing a nuclear localization signal followed by an invariant N-x7-R/K motif that contacts the DNA; and, second, a heptad repeat of leucines or other bulky hydrophobic amino acids positioned exactly nine amino acids towards the C-terminus, creating an amphipathic helix. To bind DNA, two subunits adhere via interactions between the hydrophobic sides of their helices, which creates a superimposing coiled-coil structure. The ability to form homo- and heterodimers is influenced by the electrostatic attraction and repulsion of polar residues flanking the hydrophobic interaction surface of the helices.

Plant bZIP proteins preferentially bind to DNA sequences with an ACGT core. Binding specificity is regulated by flanking nucleotides. Plant bZIPs preferentially bind to the A-box (TACGTA), C-box (GACGTC) and G-box (CACGTG), but there are also examples of nonpalindromic binding sites.

Jakoby M, Weisshaar B, Droge-Laser W, Vicente-Carbajosa J, Tiedemann J, Kroj T, Parcy F
bZIP transcription factors in Arabidopsis.
Trends Plant Sci, 2002. 7(3): p. 106-11.
PMID: 11906833