PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Arabidopsis lyrata
HB-other Family
Species TF ID Description
473061HB-other family protein
479338HB-other family protein
487959HB-other family protein
494576HB-other family protein
856290HB-other family protein
880806HB-other family protein
911877HB-other family protein
911958HB-other family protein
HB-other Family Introduction

A homeobox (HB) encodes a protein domain, the homeodomain (HD), which is a conserved 60-amino acid motif present in transcription factors found in all the eukaryotic organisms. This 60-amino acid sequence folds into a characteristic three-helix structure that is able to interact specifically with DNA. Most HDs are able to bind DNA as monomers with high affinity, through interactions made by helix III (the so-called recognition helix) and a disordered N-terminal arm located beyond helix I. The high degree of conservation of this type of domain among diverse proteins from different kingdoms indicates that this structure is crucial to maintain the HD functionality and that the role played by this domain is vital.

Ariel FD, Manavella PA, Dezar CA, Chan RL.
The true story of the HD-Zip family.
Trends Plant Sci, 2007. 12(9): p. 419-26.
PMID: 17698401


Note: In plantTFDB, proteins of HB-other family include HB superfamily proteins that cannot be classified as HD-ZIP, TALE, WOX and HB-PHD.