PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Arabidopsis lyrata
ERF Family
Species TF ID Description
312283ERF family protein
315617ERF family protein
316902ERF family protein
326806ERF family protein
332869ERF family protein
332870ERF family protein
358858ERF family protein
470149ERF family protein
470633ERF family protein
471409ERF family protein
471442ERF family protein
471733ERF family protein
472144ERF family protein
472427ERF family protein
472454ERF family protein
472549ERF family protein
472824ERF family protein
473024ERF family protein
473050ERF family protein
473051ERF family protein
473706ERF family protein
473823ERF family protein
474053ERF family protein
474196ERF family protein
474440ERF family protein
474912ERF family protein
475045ERF family protein
475977ERF family protein
476245ERF family protein
476276ERF family protein
476281ERF family protein
476631ERF family protein
476698ERF family protein
476884ERF family protein
476928ERF family protein
476975ERF family protein
478447ERF family protein
479554ERF family protein
479836ERF family protein
479837ERF family protein
480862ERF family protein
481204ERF family protein
481434ERF family protein
482050ERF family protein
482320ERF family protein
482537ERF family protein
482845ERF family protein
483623ERF family protein
483781ERF family protein
483933ERF family protein
485380ERF family protein
486209ERF family protein
486521ERF family protein
486651ERF family protein
487335ERF family protein
487556ERF family protein
487996ERF family protein
488151ERF family protein
488739ERF family protein
489371ERF family protein
489689ERF family protein
489952ERF family protein
490762ERF family protein
491962ERF family protein
492279ERF family protein
492491ERF family protein
493126ERF family protein
493127ERF family protein
493200ERF family protein
493551ERF family protein
494253ERF family protein
494254ERF family protein
494572ERF family protein
495065ERF family protein
495189ERF family protein
496326ERF family protein
496327ERF family protein
496690ERF family protein
497440ERF family protein
856016ERF family protein
861519ERF family protein
862319ERF family protein
870458ERF family protein
870655ERF family protein
875616ERF family protein
887537ERF family protein
887599ERF family protein
888596ERF family protein
888650ERF family protein
889793ERF family protein
890210ERF family protein
890960ERF family protein
891481ERF family protein
892441ERF family protein
897690ERF family protein
897795ERF family protein
897935ERF family protein
897996ERF family protein
898836ERF family protein
900468ERF family protein
900671ERF family protein
902763ERF family protein
903325ERF family protein
903921ERF family protein
904766ERF family protein
908707ERF family protein
909345ERF family protein
909855ERF family protein
910017ERF family protein
910177ERF family protein
912253ERF family protein
912628ERF family protein
912950ERF family protein
913157ERF family protein
913363ERF family protein
913731ERF family protein
914837ERF family protein
917307ERF family protein
918237ERF family protein
918241ERF family protein
918406ERF family protein
919438ERF family protein
919839ERF family protein
919990ERF family protein
ERF Family Introduction

The AP2/ERF superfamily is defined by the AP2/ERF domain, which consists of about 60 to 70 amino acids and is involved in DNA binding. These three families have been defined as follows. The AP2 family proteins contain two repeated AP2/ERF domains, the ERF family proteins contain a single AP2/ERF domain, and the RAV family proteins contain a B3 domain, which is a DNA-binding domain conserved in other plant-specific transcription factors, in addition to the single AP2/ERF domain.

It has been demonstrated that the AP2/ERF proteins have important functions in the transcriptional regulation of a variety of biological processes related to growth and development, as well as various responses to environmental stimuli.

After finding the tobacco ERFs, many proteins in the ERF family were identified and implicated in many diverse functions in cellular processes, such as hormonal signal transduction, response to biotic and abiotic stresses, regulation of metabolism, and in developmental processes in various plant species.

Toshitsugu Nakano, Kaoru Suzuki, Tatsuhito Fujimura, and Hideaki Shinshi.
Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
Plant Physiol, 2006. 140(2): p. 411-32.
PMID: 16407444


The first class are proteins which bind to ethylene response elements (ERE) or GCC boxes (tobacco EREBPs, Arabidopsis AtEBP and AtERF1-5, and tomato Pti4-6) found in the promoters of ethylene-inducible pathogenesis related genes. The GCC box is an 11 bp sequence (TAAGAGCCGCC) with a core GCCGCC sequence that is required for binding.
The second class includes proteins that bind to the C-repeat or dehydration response element (DRE) in the promoters of genes that are turned on in response to low temperatures and/or water deficit (CBF1, CBF2, CBF3/DREB1A and DREB2A). The C-repeat/DREs contain the core sequence CCGAC.

Nole-Wilson S, Krizek BA.
DNA binding properties of the Arabidopsis floral development protein AINTEGUMENTA.
Nucleic Acids Res. 2000 Nov 1;28(21):4076-82. Erratum in: Nucleic Acids Res 2001 Mar 1;29(5):1261.
PMID: 11058102