PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Arachis ipaensis
bHLH Family
Species TF ID Description
Araip.007DKbHLH family protein
Araip.0158UbHLH family protein
Araip.03FDBbHLH family protein
Araip.03YVCbHLH family protein
Araip.07856bHLH family protein
Araip.0B5Q5bHLH family protein
Araip.0G2T6bHLH family protein
Araip.0HI1AbHLH family protein
Araip.0S602bHLH family protein
Araip.0T7XCbHLH family protein
Araip.12TI6bHLH family protein
Araip.13D8CbHLH family protein
Araip.1B22DbHLH family protein
Araip.1E1W9bHLH family protein
Araip.28KZQbHLH family protein
Araip.2A2GHbHLH family protein
Araip.2LX3XbHLH family protein
Araip.2U2B9bHLH family protein
Araip.37BUFbHLH family protein
Araip.42MZKbHLH family protein
Araip.438GZbHLH family protein
Araip.44BHEbHLH family protein
Araip.4C1AUbHLH family protein
Araip.4U4XRbHLH family protein
Araip.510K0bHLH family protein
Araip.52XKKbHLH family protein
Araip.5E3CZbHLH family protein
Araip.5HP4HbHLH family protein
Araip.60UY0bHLH family protein
Araip.6K1VAbHLH family protein
Araip.6Q4X9bHLH family protein
Araip.6S5NPbHLH family protein
Araip.6VX9HbHLH family protein
Araip.74SLFbHLH family protein
Araip.778BRbHLH family protein
Araip.78HJ7bHLH family protein
Araip.7B3CCbHLH family protein
Araip.7C9L6bHLH family protein
Araip.7G5H2bHLH family protein
Araip.7P91SbHLH family protein
Araip.807VLbHLH family protein
Araip.81R1ZbHLH family protein
Araip.865PMbHLH family protein
Araip.86J2TbHLH family protein
Araip.8H1P2bHLH family protein
Araip.8I39NbHLH family protein
Araip.8JJ8BbHLH family protein
Araip.8M056bHLH family protein
Araip.8T85IbHLH family protein
Araip.8W8RTbHLH family protein
Araip.97C7EbHLH family protein
Araip.9H3WYbHLH family protein
Araip.A522UbHLH family protein
Araip.A8YH6bHLH family protein
Araip.AK8SSbHLH family protein
Araip.AKW6FbHLH family protein
Araip.AR8NTbHLH family protein
Araip.AVK7QbHLH family protein
Araip.B52UHbHLH family protein
Araip.B5XPZbHLH family protein
Araip.B6R33bHLH family protein
Araip.C575SbHLH family protein
Araip.C9ZKHbHLH family protein
Araip.CAS5BbHLH family protein
Araip.CX0J5bHLH family protein
Araip.D3S94bHLH family protein
Araip.DH5CEbHLH family protein
Araip.DHX2RbHLH family protein
Araip.DYV42bHLH family protein
Araip.E31CJbHLH family protein
Araip.E7Y1XbHLH family protein
Araip.EQ8VBbHLH family protein
Araip.ERC12bHLH family protein
Araip.EV6ELbHLH family protein
Araip.F1H86bHLH family protein
Araip.FG0DMbHLH family protein
Araip.FH6APbHLH family protein
Araip.G4UQ7bHLH family protein
Araip.G8G7YbHLH family protein
Araip.GCJ0XbHLH family protein
Araip.GQB2PbHLH family protein
Araip.H4PZ4bHLH family protein
Araip.HA94CbHLH family protein
Araip.HWR4ZbHLH family protein
Araip.I1L37bHLH family protein
Araip.I1NK2bHLH family protein
Araip.I62ZTbHLH family protein
Araip.IBY8NbHLH family protein
Araip.IDV43bHLH family protein
Araip.J3DSQbHLH family protein
Araip.J3ZJDbHLH family protein
Araip.JE9KXbHLH family protein
Araip.JIB5PbHLH family protein
Araip.JLE70bHLH family protein
Araip.K0K3FbHLH family protein
Araip.K2CBNbHLH family protein
Araip.K2DDFbHLH family protein
Araip.K4M50bHLH family protein
Araip.K6CZLbHLH family protein
Araip.K6RXLbHLH family protein
Araip.KNC8HbHLH family protein
Araip.L2MXTbHLH family protein
Araip.L4GEPbHLH family protein
Araip.L83F8bHLH family protein
Araip.L8LRCbHLH family protein
Araip.L8YHHbHLH family protein
Araip.L9HT2bHLH family protein
Araip.LC4KNbHLH family protein
Araip.LGM59bHLH family protein
Araip.LP6IVbHLH family protein
Araip.LV58RbHLH family protein
Araip.LW9GQbHLH family protein
Araip.M4TVLbHLH family protein
Araip.M6R3NbHLH family protein
Araip.MA0JYbHLH family protein
Araip.MHR6KbHLH family protein
Araip.MX2SJbHLH family protein
Araip.MY2WLbHLH family protein
Araip.N5MMKbHLH family protein
Araip.NA6B3bHLH family protein
Araip.P4GTDbHLH family protein
Araip.P7G4IbHLH family protein
Araip.PF3JCbHLH family protein
Araip.PFD9BbHLH family protein
Araip.PUL8HbHLH family protein
Araip.PVV4QbHLH family protein
Araip.Q7CA9bHLH family protein
Araip.Q7H3VbHLH family protein
Araip.QB13BbHLH family protein
Araip.QJL2AbHLH family protein
Araip.R44YWbHLH family protein
Araip.RAG9JbHLH family protein
Araip.RM65AbHLH family protein
Araip.RMK33bHLH family protein
Araip.RX20ZbHLH family protein
Araip.SB6JFbHLH family protein
Araip.SS15EbHLH family protein
Araip.UAK9JbHLH family protein
Araip.UC4CTbHLH family protein
Araip.UL9LCbHLH family protein
Araip.UT46IbHLH family protein
Araip.UVF95bHLH family protein
Araip.V1VB7bHLH family protein
Araip.V8XWPbHLH family protein
Araip.VCZ4RbHLH family protein
Araip.W1EXIbHLH family protein
Araip.W4GJ9bHLH family protein
Araip.W6M4VbHLH family protein
Araip.WC91UbHLH family protein
Araip.WU1YNbHLH family protein
Araip.X1DK4bHLH family protein
Araip.X1DZZbHLH family protein
Araip.X784UbHLH family protein
Araip.YK053bHLH family protein
Araip.YR6Y7bHLH family protein
Araip.YT7PRbHLH family protein
Araip.Z1VRTbHLH family protein
Araip.Z8IARbHLH family protein
Araip.Z8QJXbHLH family protein
Araip.ZE5CUbHLH family protein
bHLH Family Introduction

The basic/helix-loop-helix (bHLH) proteins are a superfamily of transcription factors that have been well characterized in nonplant eukaryotes, especially in mammalian systems, in which considerable structural, functional, and phylogenetic analyses have been performed. The data indicate that bHLH proteins are important regulatory components in transcriptional networks in these systems, controlling a diversity of processes from cell proliferation to cell lineage establishment.

This family is defined by the bHLH signature domain, which consists of 60 amino acids with two functionally distinct regions. The basic region, located at the N-terminal end of the domain, is involved in DNA binding and consists of 15 amino acids with a high number of basic residues. The HLH region, at the C-terminal end, functions as a dimerization domain and is constituted mainly of hydrophobic residues that form two amphipathic -helices separated by a loop region of variable sequence and length. Outside of the conserved bHLH domain, these proteins exhibit considerable sequence divergence. Cocrystal structural analysis has shown that the interaction between the HLH regions of two separate polypeptides leads to the formation of homodimers and/or heterodimers and that the basic region of each partner binds to half of the DNA recognition sequence. Some bHLH proteins form homodimers or restrict their heterodimerization activity to closely related members of the family. On the other hand, some can form heterodimers with one or several different partners.

The core DNA sequence motif recognized by the bHLH proteins is a consensus hexanucleotide sequence known as the E-box (5'-CANNTG-3'). There are different types of E-boxes, depending on the identity of the two central bases. One of the most common is the palindromic G-box (5'-CACGTG-3'). Certain conserved amino acids within the basic region of the protein provide recognition of the core consensus site, whereas other residues in the domain dictate specificity for a given type of E-box . In addition, flanking nucleotides outside of the hexanucleotide core have been shown to play a role in binding specificity, and there is evidence that a loop residue in the protein plays a role in DNA binding through elements that lie outside of the core recognition sequence.

Toledo-Ortiz G, Huq E, Quail PH.
The Arabidopsis basic/helix-loop-helix transcription factor family.
Plant Cell. 2003 Aug;15(8):1749-70
PMID: 12897250