PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Azadirachta indica
WRKY Family
Species TF ID Description
Neem_10089_f_2WRKY family protein
Neem_10258_f_1WRKY family protein
Neem_10315_f_3WRKY family protein
Neem_10594_f_1WRKY family protein
Neem_10706_f_2WRKY family protein
Neem_10925_f_1WRKY family protein
Neem_10999_f_1WRKY family protein
Neem_11104_f_2WRKY family protein
Neem_11122_f_2WRKY family protein
Neem_11232_f_2WRKY family protein
Neem_11298_f_1WRKY family protein
Neem_12888_f_1WRKY family protein
Neem_12973_f_5WRKY family protein
Neem_1476_f_4WRKY family protein
Neem_1498_f_1WRKY family protein
Neem_1639_f_10WRKY family protein
Neem_1673_f_2WRKY family protein
Neem_17452_f_1WRKY family protein
Neem_19571_f_1WRKY family protein
Neem_19819_f_1WRKY family protein
Neem_2064_f_1WRKY family protein
Neem_20658_f_1WRKY family protein
Neem_2071_f_3WRKY family protein
Neem_20756_f_1WRKY family protein
Neem_2079_f_1WRKY family protein
Neem_22740_f_1WRKY family protein
Neem_23394_f_2WRKY family protein
Neem_2350_f_4WRKY family protein
Neem_2428_f_1WRKY family protein
Neem_24714_f_1WRKY family protein
Neem_25545_f_2WRKY family protein
Neem_25624_f_1WRKY family protein
Neem_2643_f_2WRKY family protein
Neem_26620_f_1WRKY family protein
Neem_26983_f_1WRKY family protein
Neem_2710_f_3WRKY family protein
Neem_27844_f_1WRKY family protein
Neem_28800_f_1WRKY family protein
Neem_29581_f_1WRKY family protein
Neem_30360_f_2WRKY family protein
Neem_320_f_10WRKY family protein
Neem_3377_f_3WRKY family protein
Neem_34357_f_1WRKY family protein
Neem_35182_f_2WRKY family protein
Neem_35311_f_2WRKY family protein
Neem_36183_f_1WRKY family protein
Neem_3790_f_2WRKY family protein
Neem_3796_f_1WRKY family protein
Neem_38115_f_1WRKY family protein
Neem_38468_f_1WRKY family protein
Neem_38832_f_1WRKY family protein
Neem_39829_f_1WRKY family protein
Neem_40298_f_1WRKY family protein
Neem_40999_f_1WRKY family protein
Neem_41110_f_1WRKY family protein
Neem_4148_f_2WRKY family protein
Neem_42776_f_1WRKY family protein
Neem_433_f_4WRKY family protein
Neem_435_f_4WRKY family protein
Neem_4449_f_1WRKY family protein
Neem_5150_f_4WRKY family protein
Neem_5359_f_2WRKY family protein
Neem_5394_f_1WRKY family protein
Neem_5863_f_1WRKY family protein
Neem_6617_f_1WRKY family protein
Neem_686_f_1WRKY family protein
Neem_7049_f_7WRKY family protein
Neem_7205_f_1WRKY family protein
Neem_7353_f_1WRKY family protein
Neem_7549_f_2WRKY family protein
Neem_7583_f_1WRKY family protein
Neem_7738_f_5WRKY family protein
Neem_7_f_8WRKY family protein
Neem_820_f_7WRKY family protein
Neem_8542_f_7WRKY family protein
Neem_9097_f_1WRKY family protein
Neem_944_f_2WRKY family protein
Neem_9633_f_1WRKY family protein
WRKY Family Introduction

WRKY transcription factors are one of the largest families of transcriptional regulators in plants and form integral parts of signalling webs that modulate many plant processes. Here, we review recent significant progress in WRKY transcription factor research. New findings illustrate that WRKY proteins often act as repressors as well as activators, and that members of the family play roles in both the repression and de-repression of important plant processes. Furthermore, it is becoming clear that a single WRKY transcription factor might be involved in regulating several seemingly disparate processes. Mechanisms of signalling and transcriptional regulation are being dissected, uncovering WRKY protein functions via interactions with a diverse array of protein partners, including MAP kinases, MAP kinase kinases, 14-3-3 proteins, calmodulin, histone deacetylases, resistance proteins and other WRKY transcription factors. WRKY genes exhibit extensive autoregulation and cross-regulation that facilitates transcriptional reprogramming in a dynamic web with built-in redundancy.

The defining feature of WRKY transcription factors is their DNA binding domain. This is called the WRKY domain after the almost invariant WRKY amino acid sequence at the N-terminus. In a few WRKY proteins, the WRKY amino acid sequences have been replaced by WRRY, WSKY, WKRY, WVKY or WKKY. The WRKY domain is about 60 residues in length, and as well as containing the WRKY signature it also has an atypical zinc-finger structure at the C-terminus. The zinc-finger structure is either Cx4-5Cx22-23HxH or Cx7Cx23HxC. Initially, in the absence of a complete gene family from any plant species, the WRKY transcription factors were divided into three groups based on the number of WRKY domains (two domains in Group I proteins and one in the others) and the structure of their zinc fingers (C2HC in Group III proteins).

Rushton PJ, Somssich IE, Ringler P, Shen QJ.
WRKY transcription factors.
Trends Plant Sci, 2010. 15(5): p. 247-58.
PMID: 20304701