PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Azadirachta indica
TCP Family
Species TF ID Description
Neem_10310_f_2TCP family protein
Neem_10812_f_1TCP family protein
Neem_11793_f_1TCP family protein
Neem_11937_f_2TCP family protein
Neem_13954_f_1TCP family protein
Neem_14419_f_1TCP family protein
Neem_16870_f_1TCP family protein
Neem_22949_f_1TCP family protein
Neem_2528_f_4TCP family protein
Neem_25973_f_2TCP family protein
Neem_28216_f_1TCP family protein
Neem_31015_f_1TCP family protein
Neem_3175_f_1TCP family protein
Neem_3188_f_1TCP family protein
Neem_3547_f_1TCP family protein
Neem_3607_f_1TCP family protein
Neem_36834_f_1TCP family protein
Neem_3947_f_8TCP family protein
Neem_6786_f_2TCP family protein
Neem_7125_f_1TCP family protein
Neem_8223_f_1TCP family protein
Neem_834_f_2TCP family protein
Neem_8773_f_6TCP family protein
TCP Family Introduction

The TCP gene family was first described in 1999, as a small group of plant genes encoding proteins sharing the socalled TCP domain, a 59-amino acid basic helix-loop-helix (bHLH) motif that allows DNA binding and protein-protein interactions. This domain was initially identified in four proteins encoded by apparently unrelated genes, from which the name 'TCP' was derived: teosinte branched1 (tb1) from maize (Zea mays), CYCLOIDEA (CYC) from snapdragon (Antirrhinum majus), and the PROLIFERATING CELL FACTORS 1 and 2 (PCF1 and PCF2) from rice (Oryza sativa). The tb1 gene is a major determinant of strong apical dominance in domesticated maize. CYC is involved in the control of floral bilateral symmetry in Antirrhinum. PCF1 and PCF2 are factors that bind to the promoter of the rice PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) gene, which encodes a protein involved in DNA replication and repair, maintenance of chromatin structure, chromosome segregation and cell-cycle progression.

TCP genes have been found in various plant species, and new roles in plant development have been elucidated. These discoveries emphasize the importance of this plant-specific gene family in the evolution and developmental control of plant form.

Martin-Trillo M, Cubas P.
TCP genes: a family snapshot ten years later.
Trends Plant Sci, 2010. 15(1): p. 31-9.
PMID: 19963426