PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Azadirachta indica
ARF Family
Species TF ID Description
Neem_11185_f_1ARF family protein
Neem_16670_f_1ARF family protein
Neem_17933_f_1ARF family protein
Neem_18423_f_1ARF family protein
Neem_20361_a_2ARF family protein
Neem_22509_f_1ARF family protein
Neem_23307_f_1ARF family protein
Neem_25293_f_1ARF family protein
Neem_25428_f_1ARF family protein
Neem_28680_f_1ARF family protein
Neem_3042_f_10ARF family protein
Neem_30902_f_1ARF family protein
Neem_31049_f_1ARF family protein
Neem_31256_f_1ARF family protein
Neem_32147_f_1ARF family protein
Neem_3242_f_8ARF family protein
Neem_3272_f_3ARF family protein
Neem_3564_f_2ARF family protein
Neem_3631_f_4ARF family protein
Neem_3752_f_1ARF family protein
Neem_3929_f_1ARF family protein
Neem_4289_f_1ARF family protein
Neem_5632_f_1ARF family protein
Neem_654_f_1ARF family protein
Neem_7256_f_2ARF family protein
Neem_7295_f_1ARF family protein
Neem_845_f_1ARF family protein
ARF Family Introduction

Auxin response factors (ARF) are transcription factors that regulate the expression of auxin response genes. ARFs bind with specificity to TGTCTC auxin response elements (AuxRE) in promoters of these genes and function in combination with Aux/IAA (auxin/indole acetic acid) repressors, which dimerize with ARF activators in an auxin-regulated manner.

Most ARFs consist of an amino-terminal DNA-binding domain (DBD), a middle region that functions as an activation domain (AD) or repression domain (RD), and a carboxy-terminal dimerization domain (CTD). The ARF DBD is classified as a plant-specific B3-type, but requires additional amino-terminal and carboxy-terminal amino acids for efficient in vitro binding to TGTCTC AuxREs.

The ARF ADs and RDs are located just carboxy-terminal to the DBDs and contain biased amino acid sequences. ARF ADs are enriched in glutamine along with serine and leucine residues, while ARF RDs are enriched in serine, proline, leucine and glycine residues.

Guilfoyle TJ, Hagen G.
Auxin response factors.
Curr Opin Plant Biol, 2007. 10(5): p. 453-60.
PMID: 17900969