PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Amaranthus hypochondriacus
ARF Family
Species TF ID Description
AHYPO_000564-RAARF family protein
AHYPO_001331-RAARF family protein
AHYPO_001335-RAARF family protein
AHYPO_001674-RAARF family protein
AHYPO_001835-RAARF family protein
AHYPO_003325-RAARF family protein
AHYPO_003480-RAARF family protein
AHYPO_007804-RAARF family protein
AHYPO_009798-RAARF family protein
AHYPO_015382-RAARF family protein
AHYPO_015942-RAARF family protein
AHYPO_016625-RAARF family protein
AHYPO_016697-RAARF family protein
AHYPO_017867-RAARF family protein
AHYPO_018273-RAARF family protein
AHYPO_018275-RAARF family protein
AHYPO_018276-RAARF family protein
AHYPO_019061-RAARF family protein
AHYPO_020239-RAARF family protein
AHYPO_020241-RAARF family protein
AHYPO_021998-RAARF family protein
AHYPO_021999-RAARF family protein
AHYPO_022000-RAARF family protein
ARF Family Introduction

Auxin response factors (ARF) are transcription factors that regulate the expression of auxin response genes. ARFs bind with specificity to TGTCTC auxin response elements (AuxRE) in promoters of these genes and function in combination with Aux/IAA (auxin/indole acetic acid) repressors, which dimerize with ARF activators in an auxin-regulated manner.

Most ARFs consist of an amino-terminal DNA-binding domain (DBD), a middle region that functions as an activation domain (AD) or repression domain (RD), and a carboxy-terminal dimerization domain (CTD). The ARF DBD is classified as a plant-specific B3-type, but requires additional amino-terminal and carboxy-terminal amino acids for efficient in vitro binding to TGTCTC AuxREs.

The ARF ADs and RDs are located just carboxy-terminal to the DBDs and contain biased amino acid sequences. ARF ADs are enriched in glutamine along with serine and leucine residues, while ARF RDs are enriched in serine, proline, leucine and glycine residues.

Guilfoyle TJ, Hagen G.
Auxin response factors.
Curr Opin Plant Biol, 2007. 10(5): p. 453-60.
PMID: 17900969