PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Arachis duranensis
bHLH Family
Species TF ID Description
Aradu.01B4CbHLH family protein
Aradu.023N4bHLH family protein
Aradu.0572CbHLH family protein
Aradu.065GYbHLH family protein
Aradu.0K58LbHLH family protein
Aradu.10L0HbHLH family protein
Aradu.1124EbHLH family protein
Aradu.1M0AQbHLH family protein
Aradu.1QN19bHLH family protein
Aradu.25NPVbHLH family protein
Aradu.277PJbHLH family protein
Aradu.29A27bHLH family protein
Aradu.33ULWbHLH family protein
Aradu.38JU0bHLH family protein
Aradu.394BEbHLH family protein
Aradu.3DA1QbHLH family protein
Aradu.45U0DbHLH family protein
Aradu.47FMEbHLH family protein
Aradu.4NW8BbHLH family protein
Aradu.4P1MRbHLH family protein
Aradu.4U54RbHLH family protein
Aradu.53P8JbHLH family protein
Aradu.573UIbHLH family protein
Aradu.5CF9RbHLH family protein
Aradu.5CX4UbHLH family protein
Aradu.5E40QbHLH family protein
Aradu.5FE4YbHLH family protein
Aradu.5Q1VYbHLH family protein
Aradu.687ABbHLH family protein
Aradu.6AJ68bHLH family protein
Aradu.6E0QJbHLH family protein
Aradu.6L1EKbHLH family protein
Aradu.6PZ3XbHLH family protein
Aradu.6VX3KbHLH family protein
Aradu.752ZVbHLH family protein
Aradu.75YXPbHLH family protein
Aradu.77XDIbHLH family protein
Aradu.83N8CbHLH family protein
Aradu.85INTbHLH family protein
Aradu.8U0A6bHLH family protein
Aradu.94QSAbHLH family protein
Aradu.959KYbHLH family protein
Aradu.99532bHLH family protein
Aradu.9C8PRbHLH family protein
Aradu.9K9IHbHLH family protein
Aradu.A6WNCbHLH family protein
Aradu.A88Q7bHLH family protein
Aradu.AE9WNbHLH family protein
Aradu.ATP30bHLH family protein
Aradu.B5WG1bHLH family protein
Aradu.B69KTbHLH family protein
Aradu.B7RDXbHLH family protein
Aradu.C4XJQbHLH family protein
Aradu.C74HTbHLH family protein
Aradu.CA8XJbHLH family protein
Aradu.D3UE4bHLH family protein
Aradu.D69CUbHLH family protein
Aradu.DP2D5bHLH family protein
Aradu.DRR9KbHLH family protein
Aradu.DSN52bHLH family protein
Aradu.DZ0GEbHLH family protein
Aradu.FEY54bHLH family protein
Aradu.FJ441bHLH family protein
Aradu.FPU47bHLH family protein
Aradu.G27H3bHLH family protein
Aradu.G38MLbHLH family protein
Aradu.G837SbHLH family protein
Aradu.GH2K1bHLH family protein
Aradu.GMN2PbHLH family protein
Aradu.GY22LbHLH family protein
Aradu.H802VbHLH family protein
Aradu.HK2E0bHLH family protein
Aradu.I0YKWbHLH family protein
Aradu.I92X3bHLH family protein
Aradu.IE5XPbHLH family protein
Aradu.J80PYbHLH family protein
Aradu.JI81DbHLH family protein
Aradu.JMP75bHLH family protein
Aradu.JT48RbHLH family protein
Aradu.K00WPbHLH family protein
Aradu.K087NbHLH family protein
Aradu.K1HGSbHLH family protein
Aradu.K7LHYbHLH family protein
Aradu.K82B1bHLH family protein
Aradu.KJM0JbHLH family protein
Aradu.KM9ZAbHLH family protein
Aradu.KWH4DbHLH family protein
Aradu.L8VRBbHLH family protein
Aradu.L9W8GbHLH family protein
Aradu.LLR91bHLH family protein
Aradu.LP0MCbHLH family protein
Aradu.LS2KIbHLH family protein
Aradu.LW8Y2bHLH family protein
Aradu.LXV06bHLH family protein
Aradu.LYC6UbHLH family protein
Aradu.M594WbHLH family protein
Aradu.MB6LXbHLH family protein
Aradu.ME2Y5bHLH family protein
Aradu.MN4MZbHLH family protein
Aradu.MXV1SbHLH family protein
Aradu.N3W47bHLH family protein
Aradu.N5DK2bHLH family protein
Aradu.N5F6JbHLH family protein
Aradu.NTN47bHLH family protein
Aradu.PBW5FbHLH family protein
Aradu.Q2I1JbHLH family protein
Aradu.Q74TIbHLH family protein
Aradu.Q8Q5ZbHLH family protein
Aradu.QAB91bHLH family protein
Aradu.QK4C3bHLH family protein
Aradu.QV5DJbHLH family protein
Aradu.QW16AbHLH family protein
Aradu.RB7BNbHLH family protein
Aradu.RC5BBbHLH family protein
Aradu.RL2B3bHLH family protein
Aradu.RLC0GbHLH family protein
Aradu.S0KU9bHLH family protein
Aradu.T39L1bHLH family protein
Aradu.T3S5XbHLH family protein
Aradu.T4PBIbHLH family protein
Aradu.TC25VbHLH family protein
Aradu.TGP1VbHLH family protein
Aradu.TN75PbHLH family protein
Aradu.TQU2TbHLH family protein
Aradu.U4ABCbHLH family protein
Aradu.UB339bHLH family protein
Aradu.UKN3WbHLH family protein
Aradu.UV8L7bHLH family protein
Aradu.V3DY2bHLH family protein
Aradu.V6ZMFbHLH family protein
Aradu.V6ZNLbHLH family protein
Aradu.V7BYPbHLH family protein
Aradu.V7DVHbHLH family protein
Aradu.VS58YbHLH family protein
Aradu.VUX24bHLH family protein
Aradu.VZN92bHLH family protein
Aradu.WC9V5bHLH family protein
Aradu.WD82PbHLH family protein
Aradu.WNQ8EbHLH family protein
Aradu.WS4QWbHLH family protein
Aradu.WS4W4bHLH family protein
Aradu.WUW36bHLH family protein
Aradu.X1TYZbHLH family protein
Aradu.X5F2FbHLH family protein
Aradu.X6KLLbHLH family protein
Aradu.XA7KSbHLH family protein
Aradu.XEX7MbHLH family protein
Aradu.Y1TMXbHLH family protein
Aradu.Y3AAHbHLH family protein
Aradu.YAX06bHLH family protein
Aradu.YG73IbHLH family protein
Aradu.YKL3PbHLH family protein
Aradu.YPV42bHLH family protein
Aradu.Z40HVbHLH family protein
Aradu.Z6I4QbHLH family protein
Aradu.ZE8WSbHLH family protein
bHLH Family Introduction

The basic/helix-loop-helix (bHLH) proteins are a superfamily of transcription factors that have been well characterized in nonplant eukaryotes, especially in mammalian systems, in which considerable structural, functional, and phylogenetic analyses have been performed. The data indicate that bHLH proteins are important regulatory components in transcriptional networks in these systems, controlling a diversity of processes from cell proliferation to cell lineage establishment.

This family is defined by the bHLH signature domain, which consists of 60 amino acids with two functionally distinct regions. The basic region, located at the N-terminal end of the domain, is involved in DNA binding and consists of 15 amino acids with a high number of basic residues. The HLH region, at the C-terminal end, functions as a dimerization domain and is constituted mainly of hydrophobic residues that form two amphipathic -helices separated by a loop region of variable sequence and length. Outside of the conserved bHLH domain, these proteins exhibit considerable sequence divergence. Cocrystal structural analysis has shown that the interaction between the HLH regions of two separate polypeptides leads to the formation of homodimers and/or heterodimers and that the basic region of each partner binds to half of the DNA recognition sequence. Some bHLH proteins form homodimers or restrict their heterodimerization activity to closely related members of the family. On the other hand, some can form heterodimers with one or several different partners.

The core DNA sequence motif recognized by the bHLH proteins is a consensus hexanucleotide sequence known as the E-box (5'-CANNTG-3'). There are different types of E-boxes, depending on the identity of the two central bases. One of the most common is the palindromic G-box (5'-CACGTG-3'). Certain conserved amino acids within the basic region of the protein provide recognition of the core consensus site, whereas other residues in the domain dictate specificity for a given type of E-box . In addition, flanking nucleotides outside of the hexanucleotide core have been shown to play a role in binding specificity, and there is evidence that a loop residue in the protein plays a role in DNA binding through elements that lie outside of the core recognition sequence.

Toledo-Ortiz G, Huq E, Quail PH.
The Arabidopsis basic/helix-loop-helix transcription factor family.
Plant Cell. 2003 Aug;15(8):1749-70
PMID: 12897250