PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Aethionema arabicum
bZIP Family
Species TF ID Description
AA118G00053bZIP family protein
AA12G00046bZIP family protein
AA13G00104bZIP family protein
AA168G00010bZIP family protein
AA19G00150bZIP family protein
AA20G00053bZIP family protein
AA210G00005bZIP family protein
AA21G00036bZIP family protein
AA21G00361bZIP family protein
AA23G00087bZIP family protein
AA26G00433bZIP family protein
AA26G00601bZIP family protein
AA2G00098bZIP family protein
AA30G00112bZIP family protein
AA30G00183bZIP family protein
AA30G00282bZIP family protein
AA31G00181bZIP family protein
AA31G00416bZIP family protein
AA32G00122bZIP family protein
AA32G00292bZIP family protein
AA32G00382bZIP family protein
AA32G00593bZIP family protein
AA33G00124bZIP family protein
AA33G00153bZIP family protein
AA39G00226bZIP family protein
AA40G00028bZIP family protein
AA44G00265bZIP family protein
AA44G00380bZIP family protein
AA45G00023bZIP family protein
AA46G00051bZIP family protein
AA46G00174bZIP family protein
AA46G00175bZIP family protein
AA4G00251bZIP family protein
AA53G00422bZIP family protein
AA53G00793bZIP family protein
AA54G00004bZIP family protein
AA58G00024bZIP family protein
AA5G00193bZIP family protein
AA60G00170bZIP family protein
AA61G00129bZIP family protein
AA61G00149bZIP family protein
AA61G00245bZIP family protein
AA61G00587bZIP family protein
AA65G00368bZIP family protein
AA67G00023bZIP family protein
AA71G00021bZIP family protein
AA797G00002bZIP family protein
AA92G00007bZIP family protein
AA93G00015bZIP family protein
AA93G00023bZIP family protein
AA93G00066bZIP family protein
AA93G00267bZIP family protein
AA9G00123bZIP family protein
bZIP Family Introduction

The bZIP domain consists of two structural features located on a contiguous alpha-helix: first, a basic region of ~ 16 amino acid residues containing a nuclear localization signal followed by an invariant N-x7-R/K motif that contacts the DNA; and, second, a heptad repeat of leucines or other bulky hydrophobic amino acids positioned exactly nine amino acids towards the C-terminus, creating an amphipathic helix. To bind DNA, two subunits adhere via interactions between the hydrophobic sides of their helices, which creates a superimposing coiled-coil structure. The ability to form homo- and heterodimers is influenced by the electrostatic attraction and repulsion of polar residues flanking the hydrophobic interaction surface of the helices.

Plant bZIP proteins preferentially bind to DNA sequences with an ACGT core. Binding specificity is regulated by flanking nucleotides. Plant bZIPs preferentially bind to the A-box (TACGTA), C-box (GACGTC) and G-box (CACGTG), but there are also examples of nonpalindromic binding sites.

Jakoby M, Weisshaar B, Droge-Laser W, Vicente-Carbajosa J, Tiedemann J, Kroj T, Parcy F
bZIP transcription factors in Arabidopsis.
Trends Plant Sci, 2002. 7(3): p. 106-11.
PMID: 11906833