PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Aethionema arabicum
WRKY Family
Species TF ID Description
AA102G00247WRKY family protein
AA102G00304WRKY family protein
AA102G00343WRKY family protein
AA10G00152WRKY family protein
AA10G00404WRKY family protein
AA1278G00001WRKY family protein
AA14G00003WRKY family protein
AA15G00270WRKY family protein
AA18G00140WRKY family protein
AA19G00169WRKY family protein
AA20G00007WRKY family protein
AA21G00063WRKY family protein
AA21G00370WRKY family protein
AA21G00452WRKY family protein
AA232G00001WRKY family protein
AA246G00009WRKY family protein
AA25G00099WRKY family protein
AA25G00159WRKY family protein
AA30G00020WRKY family protein
AA31G00850WRKY family protein
AA32G00114WRKY family protein
AA32G00212WRKY family protein
AA32G00648WRKY family protein
AA32G00676WRKY family protein
AA32G01196WRKY family protein
AA38G00101WRKY family protein
AA39G00183WRKY family protein
AA3G00054WRKY family protein
AA3G00270WRKY family protein
AA3G00272WRKY family protein
AA40G00004WRKY family protein
AA40G00035WRKY family protein
AA40G00575WRKY family protein
AA46G00101WRKY family protein
AA46G00207WRKY family protein
AA46G00208WRKY family protein
AA473G00001WRKY family protein
AA47G00031WRKY family protein
AA4G00214WRKY family protein
AA53G00437WRKY family protein
AA53G00752WRKY family protein
AA53G01333WRKY family protein
AA54G00259WRKY family protein
AA54G00298WRKY family protein
AA54G00347WRKY family protein
AA54G00400WRKY family protein
AA57G00087WRKY family protein
AA57G00405WRKY family protein
AA60G00054WRKY family protein
AA61G00112WRKY family protein
AA61G00292WRKY family protein
AA6G00277WRKY family protein
AA74G00015WRKY family protein
AA74G00016WRKY family protein
AA74G00017WRKY family protein
AA74G00019WRKY family protein
AA77G00014WRKY family protein
AA8G00273WRKY family protein
WRKY Family Introduction

WRKY transcription factors are one of the largest families of transcriptional regulators in plants and form integral parts of signalling webs that modulate many plant processes. Here, we review recent significant progress in WRKY transcription factor research. New findings illustrate that WRKY proteins often act as repressors as well as activators, and that members of the family play roles in both the repression and de-repression of important plant processes. Furthermore, it is becoming clear that a single WRKY transcription factor might be involved in regulating several seemingly disparate processes. Mechanisms of signalling and transcriptional regulation are being dissected, uncovering WRKY protein functions via interactions with a diverse array of protein partners, including MAP kinases, MAP kinase kinases, 14-3-3 proteins, calmodulin, histone deacetylases, resistance proteins and other WRKY transcription factors. WRKY genes exhibit extensive autoregulation and cross-regulation that facilitates transcriptional reprogramming in a dynamic web with built-in redundancy.

The defining feature of WRKY transcription factors is their DNA binding domain. This is called the WRKY domain after the almost invariant WRKY amino acid sequence at the N-terminus. In a few WRKY proteins, the WRKY amino acid sequences have been replaced by WRRY, WSKY, WKRY, WVKY or WKKY. The WRKY domain is about 60 residues in length, and as well as containing the WRKY signature it also has an atypical zinc-finger structure at the C-terminus. The zinc-finger structure is either Cx4-5Cx22-23HxH or Cx7Cx23HxC. Initially, in the absence of a complete gene family from any plant species, the WRKY transcription factors were divided into three groups based on the number of WRKY domains (two domains in Group I proteins and one in the others) and the structure of their zinc fingers (C2HC in Group III proteins).

Rushton PJ, Somssich IE, Ringler P, Shen QJ.
WRKY transcription factors.
Trends Plant Sci, 2010. 15(5): p. 247-58.
PMID: 20304701