PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Arabis alpina
WRKY Family
Species TF ID Description
KFK21955.1WRKY family protein
KFK22424.1WRKY family protein
KFK23321.1WRKY family protein
KFK25103.1WRKY family protein
KFK25104.1WRKY family protein
KFK25550.1WRKY family protein
KFK25750.1WRKY family protein
KFK26392.1WRKY family protein
KFK26393.1WRKY family protein
KFK26883.1WRKY family protein
KFK27140.1WRKY family protein
KFK27696.1WRKY family protein
KFK28169.1WRKY family protein
KFK28495.1WRKY family protein
KFK28904.1WRKY family protein
KFK28937.1WRKY family protein
KFK28984.1WRKY family protein
KFK29179.1WRKY family protein
KFK29599.1WRKY family protein
KFK29678.1WRKY family protein
KFK29738.1WRKY family protein
KFK29739.1WRKY family protein
KFK29777.1WRKY family protein
KFK30520.1WRKY family protein
KFK30708.1WRKY family protein
KFK30745.1WRKY family protein
KFK30968.1WRKY family protein
KFK31038.1WRKY family protein
KFK31474.1WRKY family protein
KFK32653.1WRKY family protein
KFK32753.1WRKY family protein
KFK34897.1WRKY family protein
KFK35096.1WRKY family protein
KFK35097.1WRKY family protein
KFK35417.1WRKY family protein
KFK35571.1WRKY family protein
KFK35572.1WRKY family protein
KFK36384.1WRKY family protein
KFK36740.1WRKY family protein
KFK36945.1WRKY family protein
KFK36946.1WRKY family protein
KFK37278.1WRKY family protein
KFK37406.1WRKY family protein
KFK37572.1WRKY family protein
KFK37573.1WRKY family protein
KFK37587.1WRKY family protein
KFK37652.1WRKY family protein
KFK37880.1WRKY family protein
KFK39876.1WRKY family protein
KFK40614.1WRKY family protein
KFK41227.1WRKY family protein
KFK41402.1WRKY family protein
KFK42441.1WRKY family protein
KFK42471.1WRKY family protein
KFK44770.1WRKY family protein
KFK44771.1WRKY family protein
KFK44814.1WRKY family protein
KFK44871.1WRKY family protein
WRKY Family Introduction

WRKY transcription factors are one of the largest families of transcriptional regulators in plants and form integral parts of signalling webs that modulate many plant processes. Here, we review recent significant progress in WRKY transcription factor research. New findings illustrate that WRKY proteins often act as repressors as well as activators, and that members of the family play roles in both the repression and de-repression of important plant processes. Furthermore, it is becoming clear that a single WRKY transcription factor might be involved in regulating several seemingly disparate processes. Mechanisms of signalling and transcriptional regulation are being dissected, uncovering WRKY protein functions via interactions with a diverse array of protein partners, including MAP kinases, MAP kinase kinases, 14-3-3 proteins, calmodulin, histone deacetylases, resistance proteins and other WRKY transcription factors. WRKY genes exhibit extensive autoregulation and cross-regulation that facilitates transcriptional reprogramming in a dynamic web with built-in redundancy.

The defining feature of WRKY transcription factors is their DNA binding domain. This is called the WRKY domain after the almost invariant WRKY amino acid sequence at the N-terminus. In a few WRKY proteins, the WRKY amino acid sequences have been replaced by WRRY, WSKY, WKRY, WVKY or WKKY. The WRKY domain is about 60 residues in length, and as well as containing the WRKY signature it also has an atypical zinc-finger structure at the C-terminus. The zinc-finger structure is either Cx4-5Cx22-23HxH or Cx7Cx23HxC. Initially, in the absence of a complete gene family from any plant species, the WRKY transcription factors were divided into three groups based on the number of WRKY domains (two domains in Group I proteins and one in the others) and the structure of their zinc fingers (C2HC in Group III proteins).

Rushton PJ, Somssich IE, Ringler P, Shen QJ.
WRKY transcription factors.
Trends Plant Sci, 2010. 15(5): p. 247-58.
PMID: 20304701